Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.43 |
| ▸ | F2R | P25116 | 4/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393777 | 0.88 | ALDH1A1 (0.44) | EPHX1ALDH1A1 | |
| SCHEMBL11981542 | 0.87 | ITGB3 (0.46) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL11312652 | 0.83 | EPHX1 (0.47) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL8848118 | 0.83 | HPGD (0.56) | EPHX1ALDH1A1 | |
| SCHEMBL11690 | 0.79 | MEN1 (0.45) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL6230136 | 0.79 | TNKS2 (0.45) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL28212505 | 0.78 | ALOX15 (0.49) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6229688 | 0.77 | TNKS2 (0.44) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL5650328 | 0.77 | ITGB3 (0.47) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL27401877 | 0.76 | ITGB3 (0.41) | GNAI3GNAO1GNAI1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289772-A | PHOSPHODIESTERASE INHIBITORS | PFIZER INC. (US) | 1981-09-15 | — | — | US | disclosed |