Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31230159 | 0.77 | MAOA (0.43) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL949801 | 0.73 | LMNA (0.39) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL777177 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL3716722 | 0.71 | LMNA (0.42) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL10498281 | 0.69 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL10936991 | 0.69 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL776362 | 0.69 | MAOA (0.41) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL946994 | 0.68 | ALDH1A1 (0.41) | SMN1; SMN2HSD17B10LMNAGAAPKM | |
| SCHEMBL2954117 | 0.68 | POLB (0.39) | SMN1; SMN2MAPTHPGDMGLLHSD17B10 | |
| SCHEMBL3239182 | 0.68 | LMNA (0.43) | SMN1; SMN2HSD17B10LMNANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284766-A | Process for the preparation of cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1981-08-18 | — | — | US | disclosed |
| US-4284767-A | Process for preparing 3-carbamoyloxymethyl cephalosporins | GLAXO GROUP LIMITED (GB) | 1981-08-18 | — | — | US | disclosed |