SCHEMBL8655985

SCHEMBL8655985

Nc1ccc(N=Nc2ccccc2N)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.70
NPC1 O15118 6/20 0.70
L3MBTL1 Q9Y468 5/20 0.70
GAA P10253 2/20 0.70
MEN1 O00255 8/20 0.64
KMT2A Q03164 8/20 0.64
MAPT P10636 7/20 0.64
PKM P14618 2/20 0.64
HTT P42858 1/20 0.64
TDP1 Q9NUW8 8/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
MAPK1 P28482 6/20 0.58
CYP3A4 P08684 4/20 0.58
TSHR P16473 3/20 0.58
TP53 P04637 2/20 0.58
ALDH1A1 P00352 2/20 0.58
ATM Q13315 1/20 0.46
CA12 O43570 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29683217 1.00 RAB9A (0.70) RAB9ANPC1L3MBTL1GAAMEN1
SCHEMBL8655983 1.00 RAB9A (0.70) RAB9ANPC1L3MBTL1GAAMEN1
Alcohol SCHEMBL28559934 0.89 RAB9A (0.55) RAB9ANPC1L3MBTL1GAAMEN1
SCHEMBL11318232 0.89 MAPT (0.73) RAB9ANPC1L3MBTL1GAAMEN1
SCHEMBL29569176 0.86 NPC1 (0.76) RAB9ANPC1L3MBTL1GAAMEN1
SCHEMBL434865 0.86 NPC1 (0.76) RAB9ANPC1L3MBTL1GAAMEN1
SCHEMBL590787 0.86 NPC1 (0.76) RAB9ANPC1L3MBTL1GAAMEN1
SCHEMBL29001132 0.86 NPC1 (0.76) RAB9ANPC1L3MBTL1GAAMEN1
Ammonia Solution, Strong SCHEMBL27700309 0.84 NPC1 (0.73) RAB9ANPC1L3MBTL1GAAMEN1
Hydrochloric Acid SCHEMBL11330488 0.84 NPC1 (0.73) RAB9ANPC1L3MBTL1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945758-A High-heat-conductivity graphite film and preparation method and application thereof 四川大学 2024-04-30 CN claimed
CN-117645296-B High-heat-conductivity aromatic heterocyclic polymer-based graphite film and preparation method thereof 四川大学 2024-04-12 CN claimed
CN-117645296-A High-heat-conductivity aromatic heterocyclic polymer-based graphite film and preparation method thereof 四川大学 2024-03-05 CN claimed
US-5721324-A ADDITION POLYMERIZATION SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-02-24 US claimed
EP-0026088-B1 PHOTORESIST COMPOSITIONS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-11-23 EP claimed
US-4349619-A CONTAINING ANTIHALATION AGENTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US claimed
EP-0026088-A2 Photoresist compositions JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-01 EP claimed
CN-117945758-A High-heat-conductivity graphite film and preparation method and application thereof 四川大学 2024-04-30 CN disclosed
CN-117645296-B High-heat-conductivity aromatic heterocyclic polymer-based graphite film and preparation method thereof 四川大学 2024-04-12 CN disclosed
CN-117645296-A High-heat-conductivity aromatic heterocyclic polymer-based graphite film and preparation method thereof 四川大学 2024-03-05 CN disclosed
CN-101654566-A Monoazo type composition dye YUAN DONG 2010-02-24 CN disclosed
US-5721324-A ADDITION POLYMERIZATION SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-02-24 US disclosed
US-4630621-A Method and composition for simultaneously permanently waving and dyeing human hair PONTANI SUSANNE 1986-12-23 US disclosed
EP-0109624-A2 Process for producing shaped articles made from polyurethane-polyurea which may be cellular BASF Aktiengesellschaft (DE) 1984-05-30 EP disclosed
US-4271288-A TETRACARBOXYLIC ACID BONDED TO ARYLENE MOIETY VIA METHYLENE GROUPS THE DOW CHEMICAL COMPANY (US) 1981-06-02 US disclosed