SCHEMBL1305302

SCHEMBL1305302

C(=C/c1ccc2cc3ccc(/C=C/c4ccc(C5CCCCC5)cc4)cc3cc2c1)\c1ccc(C2CCCCC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.43
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.41
BLM P54132 1/20 0.41
GPR35 Q9HC97 1/20 0.41
BACE1 P56817 1/20 0.41
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
HDAC1 Q13547 1/20 0.38
MAPT P10636 2/20 0.37
HSP90AA1 P07900 1/20 0.37
GAA P10253 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ABL1 P00519 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1305304 1.00 RELA (0.43) RELAKMT2AMEN1NPC1POLB
SCHEMBL14558928 0.86 RELA (0.43) RELAKMT2AMEN1NPC1POLB
SCHEMBL11318771 0.85 HDAC8 (0.47) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL11318751 0.85 HDAC8 (0.47) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL14559015 0.79 RELA (0.37) RELAKMT2AMEN1NPC1POLB
SCHEMBL13242707 0.79 TRPM8 (0.38) RELAKMT2AMEN1NPC1POLB
SCHEMBL3863146 0.79 BACE1 (0.58) KMT2ABACE1HDAC8MAPTHSP90AA1
SCHEMBL10492686 0.77 HDAC8 (0.44) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL10128976 0.77 CYP19A1 (0.47) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL13636754 0.75 KMT2A (0.40) KMT2AMEN1NPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2482354-A1 Thin film transistor comprising novel conductor and dielectric compositions E. I. du Pont de Nemours and Company (US) 2012-08-01 EP disclosed
EP-2482355-A1 Thin film transistor comprising novel conductor and dielectric compositions E. I. du Pont de Nemours and Company (US) 2012-08-01 EP disclosed
US-8053840-B2 Thin film transistor comprising novel conductor and dielectric compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-08 US disclosed
US-20090179198-A1 THIN FILM TRANSISTOR COMPRISING NOVEL CONDUCTOR AND DIELECTRIC COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-07-16 US disclosed
US-7528448-B2 Thin film transistor comprising novel conductor and dielectric compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-05 US disclosed
EP-2041816-A2 THIN FILM TRANSISTOR COMPRISING NOVEL CONDUCTOR AND DIELECTRIC COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-04-01 EP disclosed
WO-2008010983-A2 THIN FILM TRANSISTOR COMPRISING NOVEL CONDUCTOR AND DIELECTRIC COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-01-24 WO disclosed
US-20080012006-A1 Thin film transistor comprising novel conductor and dielectric compositions E. I. DU PONT DE NEMOURS AND COMPANY 2008-01-17 US disclosed