SCHEMBL13636754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12292323	1.00	KMT2A (0.40)	KMT2AMEN1NPC1POLBRAB9A
	SCHEMBL12292325	0.93	TRPM8 (0.41)	KMT2AMEN1NPC1POLBRAB9A
	SCHEMBL12128481	0.89	TRPM8 (0.39)	KMT2AMEN1NPC1POLBRAB9A
	SCHEMBL23691297	0.88	HTT (0.43)	KMT2AHDAC8HDAC6HDAC1LMNA
	SCHEMBL11318771	0.88	HDAC8 (0.47)	KMT2AMEN1NPC1POLBRAB9A
	SCHEMBL11318751	0.88	HDAC8 (0.47)	KMT2AMEN1NPC1POLBRAB9A
	SCHEMBL15223122	0.86	MAOB (0.39)	KMT2AMEN1NPC1POLBRAB9A
	SCHEMBL14558928	0.83	RELA (0.43)	KMT2AMEN1NPC1POLBRAB9A
	SCHEMBL13242707	0.82	TRPM8 (0.38)	KMT2AMEN1NPC1POLBRAB9A
	SCHEMBL21173567	0.81	SLC18A3 (0.46)	KMT2ALMNAHTTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.