Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | TFEB | P19484 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179742 | 0.84 | TDP1 (0.46) | NFE2L2TDP1LMNAMYCENPP2 | |
| SCHEMBL179743 | 0.84 | TDP1 (0.46) | NFE2L2TDP1LMNAMYCENPP2 | |
| SCHEMBL11519765 | 0.84 | TDP1 (0.46) | NFE2L2TDP1LMNAMYCENPP2 | |
| SCHEMBL29367457 | 0.84 | TDP1 (0.46) | NFE2L2TDP1LMNAMYCENPP2 | |
| SCHEMBL7042983 | 0.84 | PTPN1 (0.41) | NFKB1NFE2L2TDP1JUNCA1 | |
| SCHEMBL9121673 | 0.84 | MAPT (0.58) | NFKB1NFE2L2TDP1JUNCA1 | |
| SCHEMBL9121684 | 0.84 | MAPT (0.58) | NFKB1NFE2L2TDP1JUNCA1 | |
| SCHEMBL29210389 | 0.84 | LMNA (0.41) | NFKB1NFE2L2JUNCA1CA2 | |
| SCHEMBL5145234 | 0.82 | TDP1 (0.45) | NFE2L2TDP1LMNAMYCENPP2 | |
| SCHEMBL6345694 | 0.82 | TSHR (0.46) | NFE2L2TDP1MYCENPP2RAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | disclosed |
| US-4159984-A | METAL AND PROTON DONOR | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |