Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | TFEB | P19484 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433939 | 0.84 | PTGS2 (0.41) | LMNAMAPTBRD4CREBBPPTGS2 | |
| SCHEMBL11318866 | 0.84 | NFKB1 (0.40) | LMNAMAPTNFE2L2NFKB1JUN | |
| Benzene SCHEMBL3633731 | 0.80 | MAPT (0.52) | LMNAMAPTBCAT2NFE2L2TFEB | |
| SCHEMBL17680988 | 0.77 | BRD4 (0.43) | LMNABRD4CREBBPBCAT2NFE2L2 | |
| SCHEMBL17680487 | 0.73 | BRD4 (0.40) | LMNABRD4CREBBPBCAT2NFE2L2 | |
| SCHEMBL19531650 | 0.73 | BRD4 (0.40) | BRD4CREBBPBCAT2NFE2L2HSD11B1 | |
| SCHEMBL536001 | 0.72 | LMNA (0.52) | LMNABRD4CREBBPBCAT2 | |
| SCHEMBL9121673 | 0.71 | MAPT (0.58) | LMNAMAPTNFE2L2NFKB1JUN | |
| SCHEMBL12180953 | 0.71 | BRD4 (0.42) | BRD4CREBBPNFE2L2 | |
| SCHEMBL9121684 | 0.71 | MAPT (0.58) | LMNAMAPTNFE2L2NFKB1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |