Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2507424 | 0.92 | LMNA (0.49) | LMNAPOLBGAAMAPTALDH1A1 | |
| SCHEMBL2510875 | 0.91 | PPARA (0.47) | LMNAPPARAPPARGPOLBGAA | |
| SCHEMBL2510937 | 0.89 | LMNA (0.46) | LMNAPOLBGAAMAPTALDH1A1 | |
| SCHEMBL2504905 | 0.89 | LMNA (0.46) | LMNAPPARAPPARGPOLBGAA | |
| SCHEMBL2480364 | 0.85 | LMNA (0.43) | LMNAPOLBGAAMAPTALDH1A1 | |
| SCHEMBL8778657 | 0.84 | THRA (0.56) | LMNAPPARAPPARGGAAMAPT | |
| SCHEMBL28378044 | 0.84 | LMNA (0.42) | LMNAPOLBGAAMAPTALDH1A1 | |
| SCHEMBL2480808 | 0.83 | LMNA (0.41) | LMNAPPARAPOLBGAAMAPT | |
| SCHEMBL2509866 | 0.83 | LMNA (0.41) | LMNAPPARGPOLBGAAMAPT | |
| SCHEMBL30339755 | 0.83 | LMNA (0.47) | LMNAPOLBGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292142-A | MIXTURE OF PHTHALIC ANHYDRIDE AND MALEIC ANHYDRIDE | INTERNATIONAL SYNTHETIC RUBBER CO., LTD. (GB) | 1981-09-29 | — | — | US | disclosed |