SCHEMBL8778657

SCHEMBL8778657

CCCCc1ccccc1OC(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.56
THRB P10828 1/20 0.56
NPSR1 Q6W5P4 2/20 0.56
KMT2A Q03164 3/20 0.51
MAPT P10636 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
SLC6A3 Q01959 1/20 0.50
PPARA Q07869 2/20 0.48
PPARG P37231 1/20 0.48
LMNA P02545 1/20 0.47
MEN1 O00255 2/20 0.45
JAK2 O60674 1/20 0.45
USP2 O75604 1/20 0.45
ESR1 P03372 1/20 0.45
GAA P10253 1/20 0.45
ALOX15 P16050 1/20 0.45
ESR2 Q92731 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PTGER1 P34995 1/20 0.45
PTGER4 P35408 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11579345 0.94 THRA (0.64) THRATHRBNPSR1KMT2AMAPT
SCHEMBL28345751 0.94 THRA (0.64) THRATHRBNPSR1KMT2AMAPT
SCHEMBL8390875 0.94 THRA (0.64) THRATHRBNPSR1KMT2AMAPT
SCHEMBL10922307 0.91 THRA (0.53) THRATHRBNPSR1KMT2AMAPT
SCHEMBL3760693 0.90 NPSR1 (0.58) THRATHRBNPSR1KMT2AMAPT
SCHEMBL11308887 0.88 ALOX5 (0.55) THRATHRBNPSR1KMT2AMAPT
SCHEMBL2510875 0.88 PPARA (0.47) THRATHRBNPSR1KMT2AMAPT
SCHEMBL11516354 0.87 L3MBTL1 (0.51) THRATHRBNPSR1KMT2AMAPT
SCHEMBL11450808 0.87 THRB (0.59) THRATHRBNPSR1KMT2AMAPT
SCHEMBL11513305 0.86 THRB (0.49) THRATHRBNPSR1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
EP-0813522-A1 SOLID DIACYL ORGANIC PEROXIDE DISPERSIONS Akzo Nobel N.V. (NL) 1997-12-29 EP disclosed
US-5690856-A PASTE STABILIZER AKZO NOBEL N.V. (NL) 1997-11-25 US disclosed
WO-1996027586-A1 SOLID DIACYL ORGANIC PEROXIDE DISPERSIONS AKZO NOBEL N.V. (NL) 1996-09-12 WO disclosed
US-4292142-A MIXTURE OF PHTHALIC ANHYDRIDE AND MALEIC ANHYDRIDE INTERNATIONAL SYNTHETIC RUBBER CO., LTD. (GB) 1981-09-29 US disclosed
US-4259225-A STORAGE STABILITY DAINIPPON INK & CHEMICALS, INC. (JP) 1981-03-31 US disclosed