Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | KCNJ6 | P48051 | 7/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 7/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | AKT2 | P31751 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131498 | 1.00 | CNR1 (0.43) | CNR1KCNJ6KCNJ3KCNJ5HPGD | |
| SCHEMBL3887462 | 0.89 | ALOX5 (0.45) | CNR1KCNJ6KCNJ3KCNJ5HPGD | |
| SCHEMBL3887467 | 0.89 | ALOX5 (0.45) | CNR1KCNJ6KCNJ3KCNJ5HPGD | |
| SCHEMBL1132022 | 0.88 | CMKLR1 (0.41) | CNR1KCNJ6KCNJ3KCNJ5HPGD | |
| SCHEMBL1131504 | 0.81 | CNR1 (0.43) | CNR1KCNJ6KCNJ3KCNJ5HPGD | |
| SCHEMBL1131587 | 0.79 | CMKLR1 (0.39) | CNR1KCNJ6KCNJ3KCNJ5HPGD | |
| SCHEMBL1131591 | 0.79 | CMKLR1 (0.39) | CNR1KCNJ6KCNJ3KCNJ5HPGD | |
| SCHEMBL1131971 | 0.78 | CMKLR1 (0.41) | CNR1KCNJ6KCNJ3KCNJ5HPGD | |
| SCHEMBL1131969 | 0.78 | CMKLR1 (0.41) | CNR1KCNJ6KCNJ3KCNJ5HPGD | |
| SCHEMBL1131499 | 0.75 | CNR1 (0.48) | CNR1KCNJ6KCNJ3KCNJ5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |