SCHEMBL11320488

SCHEMBL11320488

C=COCCOC(=O)OCCOC=C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
ALDH1A1 P00352 4/20 0.41
TP53 P04637 2/20 0.41
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.33
HPGD P15428 2/20 0.32
THRB P10828 2/20 0.31
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9300010 0.85 TSHR (0.48) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5382514 0.84 THRB (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5351798 0.82
SCHEMBL7111060 0.81 HDAC6 (0.33) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL1128235 0.80
SCHEMBL9068218 0.80
SCHEMBL4626289 0.80 TSHR (0.48) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL4276260 0.80 ADRA2A (0.43) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL278577 0.80 TSHR (0.67) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9622498 0.78 ALDH1A1 (0.47) ALDH1A1THRBLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112534618-A Novel electrolyte compositions for sodium-ion batteries 法国国家科学研究中心 2021-03-19 CN claimed
CN-112534618-A Novel electrolyte compositions for sodium-ion batteries 法国国家科学研究中心 2021-03-19 CN disclosed
US-4307032-A Process for the preparation of dialkyl carbonates BAYER AKTIENGESELLSCHAFT (DE) 1981-12-22 US disclosed
US-4181676-A Process for the preparation of dialkyl carbonates BAYER AKTIENGESELLSCHAFT (DE) 1980-01-01 US disclosed