Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576501 | 0.82 | NOTUM (0.51) | GAAHPGDALDH1A1HTTAPP | |
| SCHEMBL27701641 | 0.81 | GAA (0.46) | GAAHPGDALDH1A1HTTAPP | |
| Hydrochloric Acid SCHEMBL5349528 | 0.81 | NOTUM (0.50) | GAAHPGDALDH1A1HTTAPP | |
| SCHEMBL7982484 | 0.79 | HTT (0.49) | GAAHPGDALDH1A1HTTAPP | |
| SCHEMBL27837975 | 0.79 | ALDH1A1 (0.56) | GAAHPGDALDH1A1HTTKCNA5 | |
| SCHEMBL965251 | 0.78 | NOTUM (0.51) | GAAHPGDALDH1A1HTTAPP | |
| SCHEMBL14539624 | 0.78 | HTT (0.59) | GAAHPGDALDH1A1HTTKCNA5 | |
| SCHEMBL10094158 | 0.78 | GAA (0.47) | GAAHPGDALDH1A1HTTAPP | |
| SCHEMBL14817119 | 0.75 | RAB9A (0.45) | GAAHPGDHTTNPC1RAB9A | |
| SCHEMBL9571667 | 0.75 | RAB9A (0.45) | GAAHPGDALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4296028-A | Pyrazolonyl substituted disazo pigments | BASF ITALIA SPA (IT) | 1981-10-20 | — | — | US | disclosed |
| US-4269769-A | Diazo compounds obtained by coupling acetoacetanilides with tetrazotized diaminobenzanilides | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-05-26 | — | — | US | disclosed |