Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11391950 | 0.83 | LTA4H (0.53) | MAOB | |
| SCHEMBL11326273 | 0.81 | FDFT1 (0.46) | PPARG | |
| SCHEMBL2954809 | 0.77 | LTA4H (0.60) | PARP10LPAR1LPAR5 | |
| SCHEMBL2356168 | 0.77 | CXCL8 (0.64) | PARP10SLC6A4CXCL8KDM4EFKBP1A | |
| SCHEMBL11320294 | 0.77 | FFAR4 (0.52) | SLC6A4 | |
| SCHEMBL2354368 | 0.77 | TTR (0.50) | PARP10CXCL8GCKLPAR1LPAR5 | |
| SCHEMBL6290666 | 0.75 | CXCL8 (0.46) | PARP10HTR2ASLC6A4CXCL8GCK | |
| SCHEMBL6293051 | 0.75 | PARP10 (0.66) | PARP10SLC6A4CXCL8LPAR1LPAR5 | |
| SCHEMBL2290424 | 0.74 | PARP10 (0.42) | PARP10HTR2ASLC6A4CXCL8GCK | |
| SCHEMBL6290619 | 0.74 | PARP10 (0.50) | PARP10SLC6A4CXCL8GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001064-B1 | FLUOROSUBSTITUTED PHENOXYBENZYL-OXYCARBONYLDERIVATIVES, -ALCOHOLS AND -HALIDES, PROCESSES FOR THEIR PREPARATION AND THEIR APPLICATION | BAYER AG (DE) | 1982-07-07 | — | — | EP | disclosed |
| US-4199596-A | ESTERS, INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-04-22 | — | — | US | disclosed |