SCHEMBL1132098

SCHEMBL1132098

CC(C)(C)c1ccc(OP(O)c2cccc(-c3ccccc3)c2)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.39
RXRB P28702 2/20 0.39
KIF11 P52732 1/20 0.36
APEX1 P27695 1/20 0.36
CNR1 P21554 1/20 0.35
CYP2C19 P33261 1/20 0.34
DHODH Q02127 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
IDO1 P14902 5/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30975107 0.92 CNR1 (0.35) RXRARXRBKIF11APEX1CNR1
SCHEMBL27737111 0.90 RXRA (0.38) RXRARXRBKIF11APEX1CNR1
SCHEMBL30975104 0.89 CNR1 (0.38) RXRARXRBKIF11APEX1CNR1
SCHEMBL2907692 0.87 KIF11 (0.38) RXRARXRBKIF11APEX1CYP2C19
SCHEMBL29258001 0.82 KIF11 (0.37) RXRARXRBKIF11APEX1ALDH1A1
SCHEMBL28013674 0.81 RXRA (0.38) RXRARXRBKIF11APEX1CNR1
SCHEMBL12152002 0.81 KIF11 (0.37) RXRARXRBKIF11APEX1CNR1
SCHEMBL2847662 0.80 TRPV1 (0.35) RXRARXRBKIF11APEX1CYP2C19
SCHEMBL29421633 0.80 TRPV1 (0.35) RXRARXRBKIF11APEX1CYP2C19
SCHEMBL9402856 0.80 RXRA (0.37) RXRARXRBKIF11APEX1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102112547-A Method for manufacturing molded article TEIJIN CHEMICALS LTD 2011-06-29 CN claimed
EP-2287655-B1 EYEGLASS LENS TEIJIN CHEMICALS LTD (JP) 2019-01-23 EP disclosed
CN-102015892-B Flame-retardant polycarbonate resin composition TEIJIN CHEMICALS LTD 2013-09-25 CN disclosed
CN-101641411-B Sliding resin composition and molded article thereof TEIJIN CHEMICALS LTD 2013-09-04 CN disclosed
CN-103270555-A Resin composition for coating electric wire and insulated electric wire using same TEIJIN LTD 2013-08-28 CN disclosed
CN-102471467-B Optical lens, and polyester carbonate copolymer for use in optical lenses TEIJIN CHEMICALS LTD 2013-07-17 CN disclosed
CN-101889058-B Resin composition, molded article thereof, and key of terminal device TEIJIN CHEMICALS LTD 2013-07-10 CN disclosed
US-8425032-B2 Spectacle lens TEIJIN CHEMICALS, LTD. (JP) 2013-04-23 US disclosed
CN-102112547-A Method for manufacturing molded article TEIJIN CHEMICALS LTD 2011-06-29 CN disclosed
US-20110128494-A1 SPECTACLE LENS TEIJIN CHEMICALS, LTD. (JP) 2011-06-02 US disclosed
EP-2287655-A1 EYEGLASS LENS Teijin Chemicals, Ltd. (JP) 2011-02-23 EP disclosed
CN-101519528-A Polycarbonate resin composition with superior appearance TEIJIN CHEMICALS LTD 2009-09-02 CN disclosed
CN-101466789-A Resin composition TEIJIN CHEMICALS LTD (JP) 2009-06-24 CN disclosed
CN-101434750-A Polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2009-05-20 CN disclosed
CN-101434749-A Polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2009-05-20 CN disclosed
CN-101429330-A Resin composition TEIJIN CHEMICALS LTD (JP) 2009-05-13 CN disclosed
CN-101423655-A Antiflaming optical diffusion polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2009-05-06 CN disclosed
CN-101412844-A Flame-retardant polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2009-04-22 CN disclosed