Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615609 | 0.95 | APEX1 (0.34) | RXRARXRBAPEX1KIF11CYP2C9 | |
| SCHEMBL6819958 | 0.91 | APEX1 (0.40) | RXRARXRBAPEX1KIF11CYP2C9 | |
| SCHEMBL1132092 | 0.90 | APEX1 (0.36) | RXRARXRBAPEX1KIF11CYP2C9 | |
| SCHEMBL7615315 | 0.89 | APEX1 (0.39) | RXRARXRBAPEX1KIF11CYP2C9 | |
| SCHEMBL7621153 | 0.88 | CA1 (0.33) | APEX1KIF11CA1CA2CA9 | |
| SCHEMBL27737111 | 0.87 | RXRA (0.38) | RXRARXRBAPEX1KIF11CYP2C9 | |
| SCHEMBL7644494 | 0.87 | CYP1A2 (0.35) | RXRARXRBAPEX1RARARARB | |
| SCHEMBL205802 | 0.83 | CA1 (0.35) | RXRARXRBAPEX1KIF11CA1 | |
| SCHEMBL29355846 | 0.83 | CA1 (0.35) | RXRARXRBAPEX1KIF11CA1 | |
| SCHEMBL21018012 | 0.82 | APEX1 (0.32) | RXRARXRBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281640-A | For thermoplastic or thermosetting plastics, polymer-containing polymerized mono- or diolefin molding materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-25 | — | — | US | disclosed |