Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | GLRA1 | P23415 | 14/20 | 0.73 |
| ▸ | GLRB | P48167 | 14/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | SCN1A | P35498 | 1/20 | 0.71 |
| ▸ | TAS2R46 | P59540 | 1/20 | 0.71 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.71 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Brucine SCHEMBL12293782 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL14029321 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL1648976 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL29391712 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL10307298 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL23468158 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL19476145 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL6233075 | 0.99 | TAS2R10 (0.98) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL6794678 | 0.99 | TAS2R10 (0.98) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL7253414 | 0.99 | TAS2R10 (0.98) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10105 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122005546-A | Application of brucine compounds in preparation of medicines for treating acute cerebral ischemic stroke | 皖南医学院 | 2026-05-12 | — | — | CN | claimed |
| US-20260047566-A1 | Durable and Edible Bait Roll Ups, Systems and Methods | FLORIDA INSECT CONTROL GROUP LLC (US) | 2026-02-19 | — | — | US | claimed |
| US-20260021089-A1 | APPLICATION METHOD OF BRUCINE FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS | UNIV ZHEJIANG CHINESE MEDICAL (CN) | 2026-01-22 | — | — | US | claimed |
| US-12446575-B1 | Durable and edible bait roll ups, systems and methods | FLORIDA INSECT CONTROL GROUP LLC (US) | 2025-10-21 | — | — | US | claimed |
| US-20250302794-A1 | COMPOSITIONS, METHODS AND SYSTEMS FOR THE TREATMENT OF CUTANEOUS DISORDERS | VERRICA PHARMACEUTICALS INC. (US) | 2025-10-02 | — | — | US | claimed |
| US-20250288538-A1 | ABUSE AND MISUSE DETERRENT TRANSDERMAL SYSTEMS | NUTRIBAND INC (US) | 2025-09-18 | — | — | US | claimed |
| US-20250197666-A1 | Battery Cell With Safety Layer | DURACELL U.S. OPERATIONS, INC. | 2025-06-19 | — | — | US | claimed |
| WO-2025128939-A1 | BATTERY CELL WITH SAFETY LAYER | DURACELL U.S. OPERATIONS, INC. (US) | 2025-06-19 | — | — | WO | claimed |
| WO-2025120551-A1 | INTERMEDIATE COMPOUND USED IN PREPARING HETEROCYCLE DERIVATIVE, METHOD FOR PREPARING SAME, AND METHOD FOR PREPARING HETEROCYCLE DERIVATIVE USING SAME | 제이더블유중외제약 주식회사 | 2025-06-12 | — | — | WO | claimed |
| CN-120118006-A | Sulfite compound with chirality and isomerism and application thereof | 成都瀚巢生物技术研究有限公司 | 2025-06-10 | — | — | CN | claimed |
| US-4467102-A | RACEMIC MODIFICATION WITH BRUCINE | UBE INDUSTRIES, LTD. (JP) | 1984-08-21 | — | — | US | claimed |
| US-4436823-A | COLORIMETRIC ANALYSIS | DRAGERWERK AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | claimed |
| US-4424355-A | Resolution of substituted dibenzo b,f!thiepin-3-carboxylic acid-5-oxides with brucine or ephedrine | MERCK & CO., INC. (US) | 1984-01-03 | — | — | US | claimed |
| EP-0084928-A1 | Process for producing threo-3-(3,4-dihydroxyphenyl)serine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-03 | — | — | EP | claimed |
| US-4250250-A | Photographic process | MITA INDUSTRIAL COMPANY LIMITED (JP) | 1981-02-10 | — | — | US | claimed |
| US-4224457-A | Process for manufacturing optically active sulfur-containing carboxylic acid | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1980-09-23 | — | — | US | claimed |
| US-RE29990-E | Processes for stereospecifically preparing chiral 2-substituted-4-hydroxy-2-cyclopenten-1-one | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1979-05-08 | — | — | US | claimed |
| US-4151360-A | Optically active amine salts | HOFFMANN-LA ROCHE INC. (US) | 1979-04-24 | — | — | US | claimed |
| US-4048224-A | Process for resolving alanine, 3-fluoro and 2-deutero-3-fluoro-DL-alanine | MERCK & CO., INC. (US) | 1977-09-13 | — | — | US | claimed |
| US-3968141-A | Processes for stereospecifically preparing chiral 2-substituted-4-hydroxy-2-cyclopenten-1-one | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1976-07-06 | — | — | US | claimed |