Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | GLRA1 | P23415 | 14/20 | 0.73 |
| ▸ | GLRB | P48167 | 14/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | SCN1A | P35498 | 1/20 | 0.71 |
| ▸ | TAS2R46 | P59540 | 1/20 | 0.71 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.71 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Brucine SCHEMBL113229 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL29391712 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL10307298 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL14029321 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL19476145 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL23468158 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL12293782 | 1.00 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL6233075 | 0.99 | TAS2R10 (0.98) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL6794678 | 0.99 | TAS2R10 (0.98) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL7253414 | 0.99 | TAS2R10 (0.98) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118731212-A | Method for measuring alkaloid content in cosmetics by ultra-high performance liquid chromatography-four-level rod time-of-flight high-resolution mass spectrometry | 中国食品药品检定研究院(国家药品监督管理局医疗器械标准管理中心、中国药品检验总所) | 2024-10-01 | — | — | CN | disclosed |
| CN-117463297-A | Mass spectrum detection method of strychnine and adsorption purification composition used by same | 浙江树人学院 | 2024-01-30 | — | — | CN | disclosed |
| CN-114441663-A | Method for screening protein positive compounds by using solid phase microextraction affinity selection mass spectrum | 中国科学院上海药物研究所 | 2022-05-06 | — | — | CN | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |