Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324632 | 0.86 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPTLMNAALOX12ALDH1A1 | |
| SCHEMBL11369719 | 0.78 | CYP3A4 (0.34) | SMN1; SMN2MAPTLMNAACHE | |
| SCHEMBL11324803 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTLMNAALOX12ALDH1A1 | |
| SCHEMBL11326434 | 0.75 | ACHE (0.39) | SMN1; SMN2MAPTLMNAALOX12ALDH1A1 | |
| SCHEMBL11317906 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2MAPTLMNAALOX12ALDH1A1 | |
| SCHEMBL11369717 | 0.73 | CYP3A4 (0.53) | SMN1; SMN2MAPTLMNAACHE | |
| SCHEMBL11103663 | 0.73 | GLS (0.41) | SMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL11323776 | 0.73 | — | — | |
| SCHEMBL10425817 | 0.72 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTLMNAALOX12ALDH1A1 | |
| SCHEMBL11314873 | 0.70 | MAPT (0.35) | SMN1; SMN2MAPTLMNAALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307101-A | ANTIHISTAMINES AND ANTISECRETORY AGENTS OF THE THIOUREA OR UREA DERIVATIVES 5,6,7,8-TETRAHYDROIMIDAZO(1,5A)PYRIDINE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-12-22 | — | — | US | disclosed |
| US-4293697-A | ANTIHISTAMINES | SMITH, KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4230865-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-28 | — | — | US | disclosed |
| US-4226874-A | ANTIHISTAMINES, ANTISECRETORY AGENTS, GASTRIC JUICE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-07 | — | — | US | disclosed |
| US-4151288-A | ANTHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-04-24 | — | — | US | disclosed |
| US-4137234-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4018931-A | INHIBITION OF H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-04-19 | — | — | US | disclosed |
| US-3950353-A | HISTAMINE INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |