Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324746 | 1.00 | AKR1C3 (0.48) | AKR1C3AKR1C2SLC6A19CYP2C9CYP1A2 | |
| SCHEMBL12499782 | 0.88 | AKR1C3 (0.50) | AKR1C3AKR1C2SLC6A19CYP2C9CYP1A2 | |
| SCHEMBL12499785 | 0.88 | AKR1C3 (0.50) | AKR1C3AKR1C2SLC6A19CYP2C9CYP1A2 | |
| SCHEMBL3256825 | 0.82 | CYP3A4 (0.59) | AKR1C3CYP2C9LMNAALDH1A1HTT | |
| SCHEMBL8858244 | 0.82 | CYP3A4 (0.59) | AKR1C3CYP2C9LMNAALDH1A1HTT | |
| SCHEMBL11337074 | 0.82 | DPEP1 (0.46) | CYP2C9LMNAPTGESALOX5PPARG | |
| SCHEMBL11340472 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2CYP2C9CYP1A2POLB | |
| SCHEMBL11337078 | 0.82 | DPEP1 (0.46) | CYP2C9LMNAPTGESALOX5PPARG | |
| SCHEMBL11340474 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2CYP2C9CYP1A2POLB | |
| SCHEMBL1655835 | 0.81 | RECQL (0.50) | AKR1C3AKR1C2SLC6A19CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273873-A | BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME | UNITIKA LTD. (JP) | 1981-06-16 | — | — | US | disclosed |