Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340474 | 1.00 | AKR1C3 (0.48) | AKR1C3PTGS2CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL3183832 | 0.88 | KMT2A (0.50) | AKR1C3PTGS2CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL11333114 | 0.88 | KMT2A (0.50) | AKR1C3PTGS2CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL8858244 | 0.82 | CYP3A4 (0.59) | AKR1C3CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL3256825 | 0.82 | CYP3A4 (0.59) | AKR1C3CYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL11324744 | 0.82 | AKR1C3 (0.48) | AKR1C3PTGS2CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL11324746 | 0.82 | AKR1C3 (0.48) | AKR1C3PTGS2CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL11337078 | 0.82 | DPEP1 (0.46) | CYP2C9LMNAPTGESALOX5PPARG | |
| SCHEMBL11337074 | 0.82 | DPEP1 (0.46) | CYP2C9LMNAPTGESALOX5PPARG | |
| SCHEMBL11329442 | 0.81 | GRIK1 (0.56) | AKR1C3CYP2C9CYP1A2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273873-A | BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME | UNITIKA LTD. (JP) | 1981-06-16 | — | — | US | disclosed |