Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337078 | 1.00 | DPEP1 (0.46) | DPEP1ALOX5PTGESPPARGCYP3A4 | |
| SCHEMBL4500806 | 0.88 | DPEP1 (0.47) | DPEP1PPARGCYP3A4CYP2C9APP | |
| SCHEMBL4500803 | 0.88 | DPEP1 (0.47) | DPEP1PPARGCYP3A4CYP2C9APP | |
| SCHEMBL3256825 | 0.82 | CYP3A4 (0.59) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL8858244 | 0.82 | CYP3A4 (0.59) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL11340472 | 0.82 | AKR1C3 (0.48) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL11340474 | 0.82 | AKR1C3 (0.48) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL11324746 | 0.82 | AKR1C3 (0.48) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL11324744 | 0.82 | AKR1C3 (0.48) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL11319892 | 0.81 | CAPN1 (0.51) | DPEP1ALOX5PTGESPPARGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273873-A | BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME | UNITIKA LTD. (JP) | 1981-06-16 | — | — | US | disclosed |