Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329439 | 0.84 | ALDH1A1 (0.57) | MAPTALDH1A1CYP2C19CYP3A4LMNA | |
| Tribuzone SCHEMBL2109159 | 0.82 | ALDH1A1 (0.52) | MAPTALDH1A1CYP2C19CYP3A4LMNA | |
| SCHEMBL11327797 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1CYP2C19CYP3A4LMNA | |
| Kebuzone SCHEMBL231224 | 0.80 | LMNA (0.58) | MAPTALDH1A1CYP2C19CYP3A4LMNA | |
| SCHEMBL11335326 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1CYP2C19CYP3A4LMNA | |
| Kebuzone SCHEMBL6375816 | 0.79 | LMNA (0.56) | MAPTALDH1A1CYP2C19CYP3A4LMNA | |
| SCHEMBL11322746 | 0.79 | ALDH1A1 (0.49) | MAPTALDH1A1CYP2C19CYP3A4LMNA | |
| SCHEMBL11327437 | 0.77 | ALDH1A1 (0.64) | MAPTALDH1A1CYP2C19CYP3A4LMNA | |
| SCHEMBL11321102 | 0.77 | ALDH1A1 (0.52) | MAPTALDH1A1CYP2C19CYP3A4LMNA | |
| SCHEMBL11332855 | 0.76 | CYP3A4 (0.51) | MAPTALDH1A1CYP2C19CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273873-A | BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME | UNITIKA LTD. (JP) | 1981-06-16 | — | — | US | disclosed |