Estradiol Dipropionate

Estradiol Dipropionate

SCHEMBL11325156

CCC(=O)Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@H](OC(=O)CC)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
KMT2A Q03164 7/20 1.00
MEN1 O00255 5/20 1.00
THRB P10828 1/20 1.00
CYP3A4 P08684 6/20 0.80
TP53 P04637 4/20 0.80
ALOX15 P16050 3/20 0.80
MAPK1 P28482 3/20 0.80
SMN1; SMN2 Q16637 5/20 0.74
ESR1 P03372 6/20 0.68
LMNA P02545 8/20 0.67
ADORA3 P0DMS8 5/20 0.67
PGR P06401 3/20 0.67
AR P10275 3/20 0.67
ATM Q13315 3/20 0.67
CHRM1 P11229 2/20 0.67
TBXA2R P21731 2/20 0.67
PTGS1 P23219 2/20 0.67
PDE3A Q14432 2/20 0.67
POLB P06746 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Estradiol Dipropionate SCHEMBL348106 1.00 MAPT (1.00) MAPTKMT2AMEN1THRBCYP3A4
Estradiol Dipropionate SCHEMBL23261681 1.00 MAPT (1.00) MAPTKMT2AMEN1THRBCYP3A4
Estradiol Dipropionate SCHEMBL30595753 1.00 MAPT (1.00) MAPTKMT2AMEN1THRBCYP3A4
Estradiol Dipropionate SCHEMBL23262384 1.00 MAPT (1.00) MAPTKMT2AMEN1THRBCYP3A4
Estradiol Dipropionate SCHEMBL5487956 0.92 MAPT (0.85) MAPTKMT2AMEN1THRBCYP3A4
Estradiol Dipropionate SCHEMBL11698942 0.91 MAPT (0.82) MAPTKMT2AMEN1THRBCYP3A4
SCHEMBL9404737 0.91 MAPT (0.83) MAPTKMT2AMEN1THRBCYP3A4
Estradiol Propionate SCHEMBL30384276 0.89 MAPT (1.00) MAPTKMT2AMEN1THRBCYP3A4
Estradiol Propionate SCHEMBL480992 0.89 MAPT (1.00) MAPTKMT2AMEN1THRBCYP3A4
Estradiol Propionate SCHEMBL30165166 0.89 MAPT (1.00) MAPTKMT2AMEN1THRBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240115490-A1 DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF LUPIN, INC. 2024-04-11 US disclosed
EP-2779996-B1 DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS UPM KYMMENE CORP (FI) 2024-04-10 EP disclosed
US-20230404911-A1 DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF LUPIN INC 2023-12-21 US disclosed
US-11389537-B2 Drug delivery system for sustained delivery of bioactive agents UPM-KYMMENE CORPORATION (FI) 2022-07-19 US disclosed
US-20200179274-A1 DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF Lupin Inc. (US) 2020-06-11 US disclosed
US-20140322327-A1 DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS UPM-KYMMENE CORPORATION (FI) 2014-10-30 US disclosed
EP-2779996-A1 DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS UPM-Kymmene Corporation (FI) 2014-09-24 EP disclosed
WO-2013072563-A1 DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS UPM-KYMMENE CORPORATION (FI) 2013-05-23 WO disclosed
US-4286587-A Vaginal drug delivery system made from polymer ALZA CORPORATION (US) 1981-09-01 US disclosed
US-4250611-A Process for making drug delivery device with reservoir ALZA CORPORATION (US) 1981-02-17 US disclosed
US-4237885-A Delivery system with mated members for storing and releasing a plurality of beneficial agents ALZA CORPORATION (US) 1980-12-09 US disclosed
US-4215691-A Vaginal contraceptive system made from block copolymer ALZA CORPORATION (US) 1980-08-05 US disclosed