Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.80 |
| ▸ | TP53 | P04637 | 4/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | ESR1 | P03372 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 8/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.67 |
| ▸ | PGR | P06401 | 3/20 | 0.67 |
| ▸ | AR | P10275 | 3/20 | 0.67 |
| ▸ | ATM | Q13315 | 3/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Estradiol Dipropionate SCHEMBL11325156 | 1.00 | MAPT (1.00) | MAPTKMT2AMEN1THRBCYP3A4 | |
| Estradiol Dipropionate SCHEMBL23261681 | 1.00 | MAPT (1.00) | MAPTKMT2AMEN1THRBCYP3A4 | |
| Estradiol Dipropionate SCHEMBL30595753 | 1.00 | MAPT (1.00) | MAPTKMT2AMEN1THRBCYP3A4 | |
| Estradiol Dipropionate SCHEMBL23262384 | 1.00 | MAPT (1.00) | MAPTKMT2AMEN1THRBCYP3A4 | |
| Estradiol Dipropionate SCHEMBL5487956 | 0.92 | MAPT (0.85) | MAPTKMT2AMEN1THRBCYP3A4 | |
| Estradiol Dipropionate SCHEMBL11698942 | 0.91 | MAPT (0.82) | MAPTKMT2AMEN1THRBCYP3A4 | |
| SCHEMBL9404737 | 0.91 | MAPT (0.83) | MAPTKMT2AMEN1THRBCYP3A4 | |
| Estradiol Propionate SCHEMBL30384276 | 0.89 | MAPT (1.00) | MAPTKMT2AMEN1THRBCYP3A4 | |
| Estradiol Propionate SCHEMBL480992 | 0.89 | MAPT (1.00) | MAPTKMT2AMEN1THRBCYP3A4 | |
| Estradiol Propionate SCHEMBL30165166 | 0.89 | MAPT (1.00) | MAPTKMT2AMEN1THRBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12310928-B2 | Enthesis healing | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2025-05-27 | — | — | US | claimed |
| EP-3886816-B1 | ESTRADIOL BENZOATE AS A STERILANT | INSIGNA INC (US) | 2023-09-13 | — | — | EP | claimed |
| US-20230226075-A1 | ANIMAL STERILIZATION BY ESTROGENIC COMPOUNDS | Insigna Inc. | 2023-07-20 | — | — | US | claimed |
| CN-116159065-A | New use of estradiol dipropionate in preventing and treating type II diabetes | 中南民族大学 | 2023-05-26 | — | — | CN | claimed |
| US-11590145-B2 | Vaginal composition comprising a combination of estrogen and vitamin D | CHEMO RESEARCH S.L. (ES) | 2023-02-28 | — | — | US | claimed |
| US-20220370474-A1 | PREVENTION OF BOAR TAINT AND AGGRESSION | Insigna Inc. | 2022-11-24 | — | — | US | claimed |
| EP-3886816-A1 | ESTRADIOL BENZOATE AS A STERILANT | Insigna Inc. (US) | 2021-10-06 | — | — | EP | claimed |
| US-11135229-B2 | Cat and dog sterilization by estrogenic compounds | Insigna Inc. (US) | 2021-10-05 | — | — | US | claimed |
| CN-113423391-A | Estradiol benzoate as infertility agent | 因斯格纳公司 | 2021-09-21 | — | — | CN | claimed |
| CN-112516149-A | Application of estradiol benzoate or pharmaceutically acceptable salt thereof in preparation of anti-coronavirus medicines | 南方医科大学 | 2021-03-19 | — | — | CN | claimed |
| US-5098714-A | OSMOTIC, ORAL DOSAGE FORM FOR FERTILITY CONTROL | ALZA CORPORATION (US) | 1992-03-24 | — | — | US | claimed |
| EP-0472645-A1 | OSMOTIC DOSAGE FORM. | ALZA CORP (US) | 1992-03-04 | — | — | EP | claimed |
| WO-1991007173-A1 | OSMOTIC, ORAL DOSAGE FORM FOR FERTILITY CONTROL | ALZA CORPORATION (US) | 1991-05-30 | — | — | WO | claimed |
| WO-1990014075-A1 | OSMOTIC DOSAGE FORM | ALZA CORPORATION (US) | 1990-11-29 | — | — | WO | claimed |
| US-4948593-A | SUSTAINED AND CONTROLLED CONTRACEPTION | ALZA CORPORATION (US) | 1990-08-14 | — | — | US | claimed |
| US-4629449-A | Vaginal dispenser for dispensing beneficial hormone | ALZA CORPORATION (US) | 1986-12-16 | — | — | US | claimed |
| US-4402695-A | Device for delivering agent in vagina | ALZA CORPORATION (US) | 1983-09-06 | — | — | US | claimed |
| US-4383993-A | PROGESTERONE, ESTRADIOL AND ESTERS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1983-05-17 | — | — | US | claimed |
| US-4346709-A | Drug delivery devices comprising erodible polymer and erosion rate modifier | ALZA CORPORATION (US) | 1982-08-31 | — | — | US | claimed |
| US-4315925-A | MAMMALIAN CONTRACEPTIVES COMPRISING PROGESTERONE AND 17B-ESTRADIOL | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1982-02-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226075-A1 | ANIMAL STERILIZATION BY ESTROGENIC COMPOUNDS | ESR1, CYP19A1, SHBG | MAPT 3203/4885KMT2A 1832/4885MEN1 1091/4885 |
| US-20220370474-A1 | PREVENTION OF BOAR TAINT AND AGGRESSION | SHBG, CYP19A1, KISS1R | MAPT 649/4885KMT2A 2536/4885MEN1 3393/4885 |
| US-11135229-B2 | Cat and dog sterilization by estrogenic compounds | CYP19A1, ESR1, SHBG | MAPT 3025/4885KMT2A 2139/4885MEN1 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.