Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191972 | 0.88 | KIF11 (0.50) | ALDH1A1MAPK1L3MBTL1FFAR1ATM | |
| SCHEMBL17119842 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1FFAR1ATM | |
| SCHEMBL11401102 | 0.81 | KIF11 (0.48) | ALDH1A1MAPK1L3MBTL1FFAR1ATM | |
| SCHEMBL3732372 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1FFAR1LDHA | |
| SCHEMBL16271059 | 0.77 | ATM (0.48) | ALDH1A1MAPK1L3MBTL1FFAR1ATM | |
| SCHEMBL3727515 | 0.76 | FFAR1 (0.60) | ALDH1A1MAPK1L3MBTL1FFAR1ATM | |
| SCHEMBL18381104 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1FFAR1HTT | |
| SCHEMBL18782519 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1FFAR1HTT | |
| SCHEMBL17119777 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1FFAR1ATM | |
| SCHEMBL2578163 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1FFAR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036713-A2 | Angiotensin converting enzyme inhibitors | UNIVERSITY OF MIAMI (US) | 1981-09-30 | — | — | EP | disclosed |
| US-4284779-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4177277-A | INHIBITION OF ANGIOTENSIN-CONVERTING ENZYME | E. R. SQUIBB & SONS, INC. (US) | 1979-12-04 | — | — | US | disclosed |