Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | TPH1 | P17752 | 1/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401102 | 0.92 | KIF11 (0.48) | KIF11LDHAATMGRM8GRM6 | |
| SCHEMBL17119842 | 0.90 | ALDH1A1 (0.46) | LDHAATMLTA4HFFAR1ALDH1A1 | |
| SCHEMBL11325192 | 0.88 | ALDH1A1 (0.43) | LDHAATMLTA4HFFAR1ALDH1A1 | |
| SCHEMBL9301762 | 0.86 | SLC1A5 (0.49) | KIF11LTA4HALDH1A1L3MBTL1NPC1 | |
| SCHEMBL432780 | 0.84 | SLC15A1 (0.55) | LTA4HALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL124385 | 0.84 | SLC15A1 (0.55) | LTA4HALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL4850398 | 0.84 | SLC15A1 (0.55) | LTA4HALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL21095358 | 0.83 | LTA4H (0.45) | LTA4HPPARGPPARA | |
| SCHEMBL16271059 | 0.83 | ATM (0.48) | LDHAATMFFAR1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL29398213 | 0.82 | SLC15A1 (0.53) | LTA4HALDH1A1MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2921482-A2 | Labeled inhibitors of prostate-specific membrane antigen (PSMA), biological evaluation, and use as imaging agents | The Johns Hopkins University (US) | 2015-09-23 | — | — | EP | disclosed |
| EP-2170075-B1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), BIOLOGICAL EVALUATION, AND USE AS IMAGING AGENTS | UNIV JOHNS HOPKINS (US) | 2014-12-03 | — | — | EP | disclosed |
| US-6030941-A | FOR DELIVERY OF DRUGS AND OTHER COMPOUNDS ACROSS LIPID LAYERS | AVI BIOPHARMA, INC. (US) | 2000-02-29 | — | — | US | disclosed |
| EP-0966303-A2 | POLYPEPTIDE CONJUGATES FOR TRANSPORTING SUBSTANCES ACROSS CELL MEMBRANES | ANTIVIRALS INC. (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1997040854-A2 | POLYPEPTIDE CONJUGATES FOR TRANSPORTING SUBSTANCES ACROSS CELL MEMBRANES | ANTIVIRALS INC. (US) | 1997-11-06 | — | — | WO | disclosed |