Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | ACACA | Q13085 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 11/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6275324 | 0.98 | ACLY (0.52) | ACLYACACBACACAPPARATTR | |
| SCHEMBL10870601 | 0.93 | ACLY (0.57) | ACLYACACBACACAPPARATTR | |
| SCHEMBL28527574 | 0.91 | ACLY (0.61) | ACLYACACBACACAPPARATTR | |
| SCHEMBL10869779 | 0.91 | ACLY (0.61) | ACLYACACBACACAPPARATTR | |
| SCHEMBL10869000 | 0.91 | ACLY (0.61) | ACLYACACBACACAPPARATTR | |
| SCHEMBL10872185 | 0.91 | ACLY (0.61) | ACLYACACBACACAPPARATTR | |
| SCHEMBL350605 | 0.84 | — | — | |
| SCHEMBL7222208 | 0.84 | ACLY (0.70) | ACLYACACBACACAPPARATTR | |
| SCHEMBL2784372 | 0.84 | ACLY (0.62) | ACLYACACBACACAPPARATTR | |
| SCHEMBL2989709 | 0.82 | ACLY (0.47) | ACLYACACBACACAPPARATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669368-B | The preparation method of high-purity low colourity Gemfibrozil Capsules | 浙江精进药业有限公司 | 2018-02-06 | — | — | CN | claimed |
| US-4665226-A | Process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid | WARNER-LAMBERT COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| CN-111728962-B | Resveratrol derivative and medical application thereof in resisting fibrosis | 绍兴君科臻元医药科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| WO-2020212955-A1 | PROCESS FOR THE PREPARATION OF A KEY INTERMEDIATE OF GEMFIBROZIL | HIKAL LIMITED (IN) | 2020-10-22 | — | — | WO | disclosed |
| WO-2019069321-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF A KEY INTERMEDIATE OF GEMFIBROZIL | HIKAL LIMITED (IN) | 2019-04-11 | — | — | WO | disclosed |
| EP-1812381-B1 | ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE | SHOWA DENKO KK (JP) | 2011-02-16 | — | — | EP | disclosed |
| US-7579066-B2 | Ethylenically unsaturated group-containing isocyanate compound and process for producing the same, and reactive monomer, reactive (meth) acrylate polymer and its use | SHOWA DENKO K.K. (JP) | 2009-08-25 | — | — | US | disclosed |
| US-20080132597-A1 | Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use | RESONAC CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-0807627-B1 | Anilide compounds as ACAT inhibitors | KOWA CO (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-6825223-B2 | ACYL COENZYME A CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS; 2-SUBSTITUTED BENZIMIDAZOLE, BENZOXAZOLE, AND BENZOTHIAZOLES | KOWA COMPANY, LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20020037910-A1 | Novel anilide compounds and pharmaceutical compositions comprising them | SHIBUYA KIMIYUKI (JP) | 2002-03-28 | — | — | US | disclosed |
| EP-0807627-A2 | Anilide compounds as ACAT inhibitors | Kowa Company Ltd. (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5641772-A | Condensed diazepinones, processes for preparing them and agents containing these compounds for treating diseases of the central nervous system and for promoting cerebral blood circulation | DR. KARL THOMAE GMBH (DE) | 1997-06-24 | — | — | US | disclosed |
| US-5610155-A | ALZHEIMER'S | DR. KARL THOMAE GMBH (DE) | 1997-03-11 | — | — | US | disclosed |
| EP-0226161-B1 | IMPROVED PROCESS FOR PREPARING 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID | WARNER-LAMBERT COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0226161-A1 | Improved process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid | WARNER-LAMBERT COMPANY (US) | 1987-06-24 | — | — | EP | disclosed |
| US-4665226-A | Process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid | WARNER-LAMBERT COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0186083-A2 | N-(2-Hyxdroxyalkyl)-amino acids and their derivatives, process for their preparation and pharmaceutical compositions containing them | ASTA Pharma AG (DE) | 1986-07-02 | — | — | EP | disclosed |
| EP-0103265-A2 | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1984-03-21 | — | — | EP | disclosed |
| US-4067726-A | 3-Ureido phenylacetamide herbicides | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037910-A1 | Novel anilide compounds and pharmaceutical compositions comprising them | ACAT1, LCAT, SOAT1 | ACLY 204/4885ACACB 58/4885ACACA 43/4885 |
| US-20080132597-A1 | Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use | ACAD9, ELOVL6, ELOVL5 | ACLY 206/4885ACACB 209/4885ACACA 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.