Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 7/20 | 0.39 |
| ▸ | HTR3A | P46098 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121152 | 0.95 | HAO1 (0.43) | HAO1TP53TDP1NPC1RAB9A | |
| SCHEMBL576257 | 0.90 | NPC1 (0.50) | HAO1TP53TDP1NPC1RAB9A | |
| SCHEMBL29411684 | 0.90 | NPC1 (0.50) | HAO1TP53TDP1NPC1RAB9A | |
| SCHEMBL29518435 | 0.80 | HSD17B10 (0.43) | TP53TDP1NPC1RAB9ALMNA | |
| SCHEMBL16768825 | 0.79 | HTR1A (0.45) | HAO1TP53TDP1NPC1RAB9A | |
| SCHEMBL76793 | 0.79 | HAO1 (0.55) | HAO1TP53TDP1HTR1AHTR3A | |
| SCHEMBL29475022 | 0.79 | HAO1 (0.55) | HAO1TP53TDP1HTR1AHTR3A | |
| SCHEMBL735441 | 0.77 | HSD17B10 (0.44) | HAO1TP53TDP1NPC1RAB9A | |
| SCHEMBL28098549 | 0.76 | HTR1A (0.47) | HAO1TP53TDP1NPC1RAB9A | |
| SCHEMBL30679505 | 0.75 | TP53 (0.48) | HAO1TP53TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4303765-A | PEPTIZATION WITH AROMATIC POLYSULFIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-01 | — | — | US | disclosed |