SCHEMBL28098549

SCHEMBL28098549

Cc1ccc(SSc2c(C)cccc2C)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 10/20 0.47
HTR3A P46098 10/20 0.47
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP1A2 P05177 4/20 0.39
CYP2A6 P11509 1/20 0.39
HAO1 Q9UJM8 1/20 0.38
ACHE P22303 1/20 0.37
ADRB2 P07550 2/20 0.36
ADRB1 P08588 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
HRH2 P25021 2/20 0.36
HTR1B P28222 2/20 0.36
HTR2A P28223 2/20 0.36
HTR2C P28335 2/20 0.36
SLC6A4 P31645 2/20 0.36
HTR7 P34969 2/20 0.36
HRH1 P35367 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29411684 0.85 NPC1 (0.50) HTR1AHTR3ANPC1RAB9ACYP1A2
SCHEMBL576257 0.85 NPC1 (0.50) HTR1AHTR3ANPC1RAB9ACYP1A2
SCHEMBL16768825 0.83 HTR1A (0.45) HTR1AHTR3ANPC1RAB9ACYP1A2
SCHEMBL11225501 0.82 HTR1A (0.59) HTR1AHTR3ACYP1A2CYP2A6HAO1
SCHEMBL9195424 0.79 ACHE (0.41) HTR1AHTR3ACYP1A2CYP2A6HAO1
SCHEMBL895629 0.78 CYP2A6 (0.47) CYP1A2CYP2A6ACHECYP3A4TDP1
SCHEMBL11325280 0.76 HAO1 (0.43) HTR1AHTR3ANPC1RAB9ACYP1A2
SCHEMBL11121152 0.76 HAO1 (0.43) HTR1AHTR3ANPC1RAB9ACYP1A2
SCHEMBL9488946 0.71 HTR1A (0.45) HTR1AHTR3ANPC1RAB9ACYP1A2
SCHEMBL13057071 0.71 HTR1A (0.57) HTR1AHTR3ACYP1A2HAO1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106104773-A Crystal growth controlling agent, p-type semiconductor microgranule or the forming method of p-type semiconductor microgranule film, hole transmission layer formation compositions and solaode 东京应化工业株式会社 2016-11-09 CN disclosed