Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.47 |
| ▸ | NOS3 | P29474 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325302 | 1.00 | NOS2 (0.47) | NOS2NOS3NOS1LMNASMN1; SMN2 | |
| SCHEMBL11325298 | 1.00 | NOS2 (0.47) | NOS2NOS3NOS1LMNASMN1; SMN2 | |
| SCHEMBL11407204 | 0.83 | RAB9A (0.48) | SMN1; SMN2L3MBTL1MAPTRAB9AKDM4E | |
| SCHEMBL11407210 | 0.83 | RAB9A (0.48) | SMN1; SMN2L3MBTL1MAPTRAB9AKDM4E | |
| SCHEMBL11407212 | 0.83 | RAB9A (0.48) | SMN1; SMN2L3MBTL1MAPTRAB9AKDM4E | |
| SCHEMBL11311798 | 0.81 | MAPT (0.45) | NOS2NOS3NOS1LMNASMN1; SMN2 | |
| SCHEMBL11311800 | 0.81 | MAPT (0.45) | NOS2NOS3NOS1LMNASMN1; SMN2 | |
| SCHEMBL11311793 | 0.81 | MAPT (0.45) | NOS2NOS3NOS1LMNASMN1; SMN2 | |
| SCHEMBL11311392 | 0.80 | MEN1 (0.49) | LMNASMN1; SMN2HPGDL3MBTL1MAPT | |
| SCHEMBL11311388 | 0.80 | MEN1 (0.49) | LMNASMN1; SMN2HPGDL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267359-A | Novel carboxylic acid esters | ZOECON CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |
| US-4204071-A | 4-Aryl-3-butenoic acids and lower alkyl esters | ZOECON CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |