SCHEMBL1132545

SCHEMBL1132545

NC(CO)CCCCCO

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.37
CYP2D6 P10635 2/20 0.37
SPHK1 Q9NYA1 1/20 0.37
GMNN O75496 1/20 0.37
POLB P06746 1/20 0.37
THPO P40225 1/20 0.37
MTOR P42345 1/20 0.37
BLM P54132 1/20 0.37
KDM4E B2RXH2 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
CETP P11597 1/20 0.37
HTT P42858 1/20 0.37
UBE2N P61088 1/20 0.37
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1131550 1.00 LMNA (0.37) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL1131594 1.00 LMNA (0.37) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL8358187 1.00 LMNA (0.37) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL28871192 1.00 LMNA (0.37) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL1132232 0.97
SCHEMBL16393049 0.97
SCHEMBL8040300 0.97
SCHEMBL1132609 0.88
SCHEMBL8668914 0.88
SCHEMBL1603970 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9949484-B2 Antimicrobial polyurethane materials and methods of forming and using same THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2018-04-24 US claimed
US-20150132248-A1 ANTIMICROBIAL POLYURETHANE MATERIALS AND METHODS OF FORMING AND USING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2015-05-14 US claimed
WO-2013166198-A1 ANTIMICROBIAL POLYURETHANE MATERIALS AND METHODS OF FORMING AND USING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2013-11-07 WO claimed
CN-116783281-A Methods and compositions for preparing amide compounds 基因组股份公司 2023-09-19 CN disclosed
US-9949484-B2 Antimicrobial polyurethane materials and methods of forming and using same THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2018-04-24 US disclosed
US-20150132248-A1 ANTIMICROBIAL POLYURETHANE MATERIALS AND METHODS OF FORMING AND USING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2015-05-14 US disclosed
WO-2013166198-A1 ANTIMICROBIAL POLYURETHANE MATERIALS AND METHODS OF FORMING AND USING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2013-11-07 WO disclosed
EP-1812381-B1 ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE SHOWA DENKO KK (JP) 2011-02-16 EP disclosed
US-7579066-B2 Ethylenically unsaturated group-containing isocyanate compound and process for producing the same, and reactive monomer, reactive (meth) acrylate polymer and its use SHOWA DENKO K.K. (JP) 2009-08-25 US disclosed
US-20080132597-A1 Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use RESONAC CORPORATION (JP) 2008-06-05 US disclosed
US-6004669-A ELECTROSTATIC CHARGING MEMBER, UNIFORMLY DISPERSED IN A MODIFIED RESIN AS A BASE POLYMER BEING MODIFIED BY AN AMINE GROUP WHICH HAS AN ACID-BASE INTERACTION WITH THE OXIDATION-PROCESSED ELECTRICALLY-CONDUCTING AGENT, FUJI XEROX CO., LTD. (JP) 1999-12-21 US disclosed
EP-0228192-A2 Renin-inhibitory oligopeptides, their preparation and use SANKYO COMPANY LIMITED (JP) 1987-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132597-A1 Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use ACAD9, ELOVL6, ELOVL5 LMNA 2468/4885CYP2D6 528/4885SPHK1 4404/4885
US-20150132248-A1 ANTIMICROBIAL POLYURETHANE MATERIALS AND METHODS OF FORMING AND USING SAME PUF60, UFL1, CUTA LMNA 3337/4885CYP2D6 3205/4885SPHK1 2238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.