Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL518236 | 0.81 | AKR1C1 (0.40) | OPRM1AKR1C1DPP4PRCPSIGMAR1 | |
| SCHEMBL6472118 | 0.78 | AKR1C1 (0.38) | OPRM1AKR1C1DPP4PRCPSIGMAR1 | |
| SCHEMBL5538611 | 0.78 | AKR1C1 (0.38) | OPRM1AKR1C1MEN1KMT2ADPP4 | |
| SCHEMBL11307986 | 0.78 | AKR1C1 (0.46) | AKR1C1MEN1KMT2AHDAC4HSD11B1 | |
| Hydrochloric Acid SCHEMBL6926723 | 0.77 | ALDH1A1 (0.39) | OPRM1AKR1C1MEN1KMT2APRCP | |
| SCHEMBL2432531 | 0.76 | TSHR (0.42) | OPRM1AKR1C1MEN1KMT2APRCP | |
| SCHEMBL2432100 | 0.75 | TSHR (0.44) | OPRM1MEN1KMT2APRCPSIGMAR1 | |
| SCHEMBL6470519 | 0.74 | TACR1 (0.35) | OPRM1AKR1C1MEN1KMT2APRCP | |
| SCHEMBL21439763 | 0.74 | SLC6A4 (0.40) | OPRM1MEN1KMT2APOLBLMNA | |
| SCHEMBL28149790 | 0.68 | AKR1C1 (0.46) | AKR1C1MEN1KMT2ADPP4HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287212-A | USEFUL AS ANALGESICS AND DIURETICS | AMERICAN HOECHST CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |