Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323565 | 0.98 | OPRM1 (0.47) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11316996 | 0.95 | OPRD1 (0.46) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11316784 | 0.94 | OPRD1 (0.45) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11309559 | 0.81 | OPRM1 (0.41) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL2515981 | 0.81 | OPRM1 (0.49) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL2518902 | 0.80 | OPRM1 (0.48) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL2518903 | 0.80 | OPRM1 (0.48) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11313951 | 0.79 | SLC6A4 (0.47) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11319376 | 0.78 | OPRM1 (0.47) | OPRM1SLC6A4SLC6A2OPRD1OPRK1 | |
| SCHEMBL11307256 | 0.78 | OPRL1 (0.47) | OPRM1SLC6A4SLC6A2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287212-A | USEFUL AS ANALGESICS AND DIURETICS | AMERICAN HOECHST CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |