Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2518902 | 0.98 | OPRM1 (0.48) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 | |
| Hydrochloric Acid SCHEMBL2518903 | 0.98 | OPRM1 (0.48) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 | |
| SCHEMBL11323565 | 0.83 | OPRM1 (0.47) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 | |
| SCHEMBL150238 | 0.82 | OPRL1 (0.44) | OPRM1SLC6A4SLC6A2OPRK1 | |
| SCHEMBL11325596 | 0.81 | OPRM1 (0.46) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 | |
| SCHEMBL8434812 | 0.81 | SLC6A2 (0.52) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 | |
| SCHEMBL5516837 | 0.81 | SLC6A2 (0.52) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 | |
| SCHEMBL11316996 | 0.79 | OPRD1 (0.46) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 | |
| Hydrochloric Acid SCHEMBL11316784 | 0.78 | OPRD1 (0.45) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 | |
| Hydrochloric Acid SCHEMBL6780753 | 0.75 | OPRK1 (0.46) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251286-A1 | Crystalline salts and/or co-crystals of O-desmethyltramadol | GRUENENTHAL GMBH (DE) | 2011-10-13 | — | — | US | disclosed |
| US-20110251286-A1 | Crystalline salts and/or co-crystals of O-desmethyltramadol | GRUENENTHAL GMBH (DE) | 2011-10-13 | — | — | US | disclosed |
| CN-1176902-C | New esters derived from substituted phenyl-cyclohexyl compounds | ά��ʵ��������˾ | 2004-11-24 | — | — | CN | disclosed |
| CN-1414946-A | Novel esters derived from (RR,SS)-2-hydroxybenzoate of 3-(2-dimethylaminomethyl-1-hydroxy cyclohexyl) phenyl | VITA INVEST SA (ES) | 2003-04-30 | — | — | CN | disclosed |
| CN-1325377-A | Novel esters derived from substituted phenyl-cyclohexyl compounds | VITA INVEST SA (ES) | 2001-12-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251286-A1 | Crystalline salts and/or co-crystals of O-desmethyltramadol | ME3, ME1, SLC16A1 | OPRM1 411/4885SLC6A4 1588/4885SLC6A2 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.