Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 10/20 | 0.52 |
| ▸ | CES1 | P23141 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325890 | 1.00 | CES2 (0.52) | CES2CES1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL8768841 | 0.80 | MAPT (0.57) | SMN1; SMN2MAPK1TDP1MAPTPKM | |
| SCHEMBL11324498 | 0.78 | CES2 (0.46) | CES2CES1SMN1; SMN2TDP1MAPT | |
| SCHEMBL11324501 | 0.78 | CES2 (0.46) | CES2CES1SMN1; SMN2TDP1MAPT | |
| SCHEMBL1370084 | 0.76 | CES2 (0.61) | CES2CES1SMN1; SMN2MAPTLMNA | |
| SCHEMBL1372210 | 0.76 | CES2 (0.61) | CES2CES1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11416768 | 0.76 | CES2 (0.61) | CES2CES1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11333722 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2MAPK1TDP1MAPTPKM | |
| SCHEMBL16279024 | 0.74 | ALDH1A1 (0.51) | CES2CES1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL91995 | 0.74 | ALDH1A1 (0.51) | CES2CES1SMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30752-E | CHEMICAL REACTANT FOR PROTECTING AMINO OR IMINO GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-29 | — | — | US | disclosed |
| US-4010178-A | Carbonic acid esters, and the preparation thereof and their use | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-03-01 | — | — | US | disclosed |