SCHEMBL8768841

SCHEMBL8768841

C/C(=N\OC(=O)Cl)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.57
PKM P14618 1/20 0.57
CDK5 Q00535 1/20 0.57
CDK5R1 Q15078 1/20 0.57
MAPK1 P28482 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
LMNA P02545 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
HTT P42858 1/20 0.53
ALDH1A1 P00352 1/20 0.49
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 1/20 0.47
HSD17B10 Q99714 1/20 0.47
POLB P06746 1/20 0.47
HPGD P15428 1/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11963959 0.84 MAPT (0.60) MAPTPKMCDK5CDK5R1MAPK1
SCHEMBL212911 0.84 MAPT (0.60) MAPTPKMCDK5CDK5R1MAPK1
SCHEMBL14667470 0.84 MAPT (0.60) MAPTPKMCDK5CDK5R1MAPK1
SCHEMBL8769756 0.83 LMNA (0.53) MAPTPKMCDK5CDK5R1MAPK1
SCHEMBL9239013 0.83 LMNA (0.53) MAPTPKMCDK5CDK5R1MAPK1
SCHEMBL92080 0.82 MAPT (0.78) MAPTPKMCDK5CDK5R1MAPK1
SCHEMBL1357956 0.82 MAPT (0.78) MAPTPKMCDK5CDK5R1MAPK1
SCHEMBL10887463 0.82 MAPT (0.51) MAPTPKMCDK5CDK5R1MAPK1
SCHEMBL11325883 0.80 CES2 (0.52) MAPTPKMCDK5CDK5R1MAPK1
SCHEMBL11325890 0.80 CES2 (0.52) MAPTPKMCDK5CDK5R1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672654-B1 Fungicidal carbamoyloxime carbonic acid amides BASF AG (DE) 1997-09-10 EP disclosed
EP-0672654-A1 Fungicidal carbamoyloxime carbonic acid amides BASF AKTIENGESELLSCHAFT (DE) 1995-09-20 EP disclosed