Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427099 | 1.00 | MAPK1 (0.54) | MAPK1ADRA2CGAAKEAP1DRD2 | |
| SCHEMBL4423797 | 0.91 | MAPK1 (0.60) | MAPK1ADRA2CGAAKEAP1DRD2 | |
| SCHEMBL26219177 | 0.87 | MAPK1 (0.70) | MAPK1ADRA2CGAAKEAP1ADRB1 | |
| SCHEMBL27934132 | 0.84 | MAPK1 (0.74) | MAPK1GAAKEAP1ALDH1A1KDM4E | |
| SCHEMBL28396664 | 0.82 | ADRB1 (0.71) | DRD2DRD3ADRB1HTTALDH1A1 | |
| SCHEMBL23152040 | 0.80 | ADRA2C (0.79) | MAPK1ADRA2CGAAKEAP1DRD2 | |
| SCHEMBL11120307 | 0.80 | GAA (0.70) | MAPK1GAAHTTALDH1A1RAB9A | |
| SCHEMBL15834279 | 0.80 | ADRB1 (0.75) | DRD2DRD3ADRB1ALDH1A1KDM4E | |
| SCHEMBL11775877 | 0.80 | ADRA2C (0.79) | MAPK1ADRA2CGAAKEAP1DRD2 | |
| SCHEMBL9424119 | 0.80 | LMNA (0.62) | GAAHTTALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4270021-A | High voltage cable splice using condensation reaction polymeric insulation | GOLD MARVIN H | 1981-05-26 | — | — | US | disclosed |
| US-4222801-A | CHAIN EXTENSION, GRAFT POLYMERIZATION | GOLD MARVIN H | 1980-09-16 | — | — | US | disclosed |