SCHEMBL11326629

SCHEMBL11326629

CCCCCCCCCCCCCCCCCCOC(=O)CCc1cc(C(C)(C)C)c(OP2Oc3ccccc3-c3ccccc32)c(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.35
P2RY10 O00398 2/20 0.34
EPHX2 P34913 2/20 0.33
CNR1 P21554 3/20 0.33
LMNA P02545 2/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11326927 0.86 PTPN11 (0.33) LMNAALDH1A1TSHR
SCHEMBL11293904 0.86 CNR2 (0.41) CNR2LMNAALDH1A1TSHR
SCHEMBL11318841 0.85 GAA (0.37) LMNAALDH1A1
SCHEMBL11294338 0.84 PTPN11 (0.35) CNR2LMNATHRATHRBALDH1A1
SCHEMBL11331777 0.83 RXRA (0.36) CNR2P2RY10LMNA
SCHEMBL10703628 0.82 PTPN1 (0.35) EPHX2ALDH1A1TDP1
SCHEMBL9658153 0.82 CNR2 (0.35) CNR2P2RY10EPHX2CNR1LMNA
SCHEMBL10633203 0.80 CNR2 (0.35) CNR2EPHX2CNR1LMNAALDH1A1
SCHEMBL10789260 0.78 DGKA (0.40) CNR2P2RY10EPHX2CNR1THRA
SCHEMBL8976831 0.77 P2RY10 (0.40) CNR2P2RY10CNR1LMNATHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0000352-B1 CYCLIC AROMATIC DIESTERS OF PHOSPHONOUS ACID AND THE ORGANIC MATERIALS STABILIZED BY THEM CIBA-GEIGY AG (CH) 1982-05-05 EP disclosed
US-4276232-A FOR PLASTICS AND ELASTOMERS CIBA-GEIGY CORPORATION (US) 1981-06-30 US disclosed
EP-0000354-A1 Mixtures that contain phosphonite, and polymers stabilized therewith CIBA-GEIGY AG (CH) 1979-01-24 EP disclosed
EP-0000352-A1 Cyclic aromatic diesters of phosphonous acid and the organic materials stabilized by them CIBA-GEIGY AG (CH) 1979-01-24 EP disclosed