SCHEMBL1132685

SCHEMBL1132685

CN(C)CCCC(O)CO

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
MAPT P10636 1/20 0.39
HTR2A P28223 1/20 0.39
HRH1 P35367 1/20 0.39
LMNA P02545 2/20 0.38
DNM1 Q05193 3/20 0.35
USP2 O75604 1/20 0.32
CYP3A4 P08684 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
HRH4 Q9H3N8 2/20 0.31
CYP1A2 P05177 1/20 0.31
HRH2 P25021 1/20 0.31
KDM4A O75164 5/20 0.31
KDM4C Q9H3R0 5/20 0.31
KDM5A P29375 1/20 0.31
KDM7A Q6ZMT4 1/20 0.31
PHF8 Q9UPP1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28581574 1.00 THRB (0.43) THRBALDH1A1TSHRMAPTHTR2A
SCHEMBL24802216 1.00 THRB (0.43) THRBALDH1A1TSHRMAPTHTR2A
SCHEMBL8885433 0.93 ALDH1A1 (0.46) THRBALDH1A1TSHRMAPTHTR2A
SCHEMBL9175539 0.91 ALDH1A1 (0.50) THRBALDH1A1TSHRMAPTLMNA
SCHEMBL9175598 0.91 ALDH1A1 (0.50) THRBALDH1A1TSHRMAPTLMNA
SCHEMBL2454527 0.87 ALDH1A1 (0.47) ALDH1A1TSHRMAPTHTR2AHRH1
Hydrochloric Acid SCHEMBL28842899 0.87 ALDH1A1 (0.46) THRBALDH1A1TSHRMAPTDNM1
SCHEMBL9671940 0.84 ALDH1A1 (0.45) ALDH1A1TSHRMAPTHTR2AHRH1
SCHEMBL943310 0.84
SCHEMBL24450550 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116064598-B Nucleic acid vaccine for coronavirus 苏州艾博生物科技有限公司 2024-03-12 CN disclosed
CN-114907243-B Ionizable lipid, composition and application thereof 东南大学 2023-10-27 CN disclosed
CN-116836074-A Ionizable lipid or pharmaceutically acceptable salt thereof, composition and application 东南大学 2023-10-03 CN disclosed
CN-116615472-A Polymer conjugated lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-08-18 CN disclosed
CN-116332830-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-06-27 CN disclosed
CN-116064598-A Nucleic acid vaccine for coronavirus 苏州艾博生物科技有限公司 2023-05-05 CN disclosed
CN-115724920-A Nucleic acid vaccine for coronavirus and influenza virus 中国人民解放军军事科学院军事医学研究院 2023-03-03 CN disclosed
CN-113874507-A Nucleic acid vaccine for coronavirus 苏州艾博生物科技有限公司 2021-12-31 CN disclosed
CN-113018449-B Cationic lipid compounds, compositions containing the same and uses thereof 苏州艾博生物科技有限公司 2021-09-07 CN disclosed
CN-112979483-B Cationic lipid compound, composition containing same and application 苏州艾博生物科技有限公司 2021-08-06 CN disclosed
CN-112979483-A Cationic lipid compound, composition containing same and application 苏州艾博生物科技有限公司 2021-06-18 CN disclosed
EP-3225621-A1 IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS Arbutus Biopharma Corporation (CA) 2017-10-04 EP disclosed
EP-2743265-B1 Improved amino lipids and methods for the delivery of nucleic acids ARBUTUS BIOPHARMA CORP (CA) 2017-03-15 EP disclosed
EP-1812381-B1 ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE SHOWA DENKO KK (JP) 2011-02-16 EP disclosed
US-7579066-B2 Ethylenically unsaturated group-containing isocyanate compound and process for producing the same, and reactive monomer, reactive (meth) acrylate polymer and its use SHOWA DENKO K.K. (JP) 2009-08-25 US disclosed
US-20080132597-A1 Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use RESONAC CORPORATION (JP) 2008-06-05 US disclosed
EP-1812381-A1 ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE SHOWA DENKO KABUSHIKI KAISHA (JP) 2007-08-01 EP disclosed
WO-2006049264-A1 ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE SHOWA DENKO K.K. (JP) 2006-05-11 WO disclosed
US-6004669-A ELECTROSTATIC CHARGING MEMBER, UNIFORMLY DISPERSED IN A MODIFIED RESIN AS A BASE POLYMER BEING MODIFIED BY AN AMINE GROUP WHICH HAS AN ACID-BASE INTERACTION WITH THE OXIDATION-PROCESSED ELECTRICALLY-CONDUCTING AGENT, FUJI XEROX CO., LTD. (JP) 1999-12-21 US disclosed
US-5925893-A POLYESTERURETHANE IONOMER FUJI XEROX CO., LTD. (JP) 1999-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132597-A1 Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use ACAD9, ELOVL6, ELOVL5 THRB 4474/4885ALDH1A1 119/4885TSHR 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.