Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337380 | 0.87 | CYP3A4 (0.42) | KMT2AHSD17B10L3MBTL1HTTALDH1A1 | |
| SCHEMBL11659521 | 0.81 | HTT (0.37) | KMT2AHSD17B10L3MBTL1HTTALDH1A1 | |
| SCHEMBL11659238 | 0.80 | TSHR (0.39) | KMT2AHSD17B10HTTALDH1A1POLB | |
| SCHEMBL11336144 | 0.80 | HPGD (0.57) | KMT2AHSD17B10HTTALDH1A1KDM4E | |
| SCHEMBL11337115 | 0.78 | TERT (0.42) | KMT2AHTTALDH1A1KDM4ENPC1 | |
| SCHEMBL11765123 | 0.78 | HDAC3 (0.49) | KMT2AHSD17B10HTTALDH1A1KDM4E | |
| SCHEMBL11435790 | 0.77 | HPGD (0.49) | KMT2AHSD17B10L3MBTL1HTTALDH1A1 | |
| SCHEMBL11328096 | 0.76 | ALDH1A1 (0.50) | KMT2AHSD17B10HTTALDH1A1POLB | |
| SCHEMBL11337741 | 0.76 | HDAC3 (0.46) | KMT2AHSD17B10L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL11665184 | 0.75 | KMT2A (0.50) | KMT2AHSD17B10L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282168-A | FUNGICIDES | PPG INDUSTRIES, INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4055657-A | S-ARYL-N-ALKYL-THIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | disclosed |