Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | UTRN | P46939 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831569 | 0.87 | LIPG (0.45) | GAAKMT2AKDM4ECACNA1BAPBA1 | |
| SCHEMBL11336489 | 0.78 | AKR1B1 (0.61) | GAAKDM4EAKR1B1NR4A1NR4A2 | |
| SCHEMBL31614347 | 0.77 | NPC1 (0.61) | GAAKMT2ASMN1; SMN2AKR1B1NR4A1 | |
| SCHEMBL3112570 | 0.77 | NPC1 (0.61) | GAAKMT2ASMN1; SMN2AKR1B1NR4A1 | |
| Water SCHEMBL21626175 | 0.75 | NPC1 (0.59) | GAAKMT2ASMN1; SMN2AKR1B1NR4A1 | |
| SCHEMBL11329003 | 0.75 | GAA (0.51) | GAAAKR1B1NR4A1NR4A2NR4A3 | |
| SCHEMBL9074105 | 0.75 | AKR1B1 (0.58) | GAAKMT2AKDM4ESMN1; SMN2AKR1B1 | |
| SCHEMBL22371424 | 0.75 | GAA (0.57) | GAAKMT2ASMN1; SMN2AKR1B1NR4A1 | |
| SCHEMBL9073764 | 0.75 | GAA (0.61) | GAAKMT2AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL11199551 | 0.75 | RAB9A (0.58) | GAAKMT2AKDM4ESMN1; SMN2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-3985763-A | DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |