Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 6/20 | 0.32 |
| ▸ | JAK1 | P23458 | 6/20 | 0.32 |
| ▸ | TYK2 | P29597 | 6/20 | 0.32 |
| ▸ | JAK3 | P52333 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973209 | 0.83 | IKBKB (0.40) | KMT2AKDM4EGLAALDH1A1SMN1; SMN2 | |
| SCHEMBL11331470 | 0.81 | TDP1 (0.37) | KMT2AFGFR1KDM4EALDH1A1SMN1; SMN2 | |
| Potassium SCHEMBL11324844 | 0.80 | TDP1 (0.36) | KMT2AFGFR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11335275 | 0.79 | HIPK2 (0.33) | — | |
| SCHEMBL11324116 | 0.73 | RXFP1 (0.36) | ALDH1A1 | |
| SCHEMBL11323158 | 0.69 | RHOA (0.41) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9227010 | 0.64 | HTR3A (0.55) | LCKCHEK2FGFR1PLAUJAK2 | |
| SCHEMBL19691192 | 0.63 | LCK (0.53) | LCKCHEK2KMT2AFGFR1PLAU | |
| SCHEMBL71079 | 0.62 | NPC1 (0.41) | KMT2AKDM4EGLAALDH1A1SMN1; SMN2 | |
| SCHEMBL14333925 | 0.62 | PSMB5 (0.50) | CHEK2KMT2AFGFR1PLAUJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250182-A | Pharmaceutical composition containing acridone compounds and method of using same | BURROUGHS WELLCOME CO. (US) | 1981-02-10 | — | — | US | disclosed |