Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | YWHAG | P61981 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331470 | 0.99 | TDP1 (0.37) | TDP1RAB9AMEN1KMT2AHTT | |
| SCHEMBL11324116 | 0.83 | RXFP1 (0.36) | TDP1RAB9AHTTRXFP1ALDH1A1 | |
| SCHEMBL11327657 | 0.80 | LCK (0.35) | KMT2AKDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11323158 | 0.79 | RHOA (0.41) | TDP1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11335275 | 0.79 | HIPK2 (0.33) | CSNK2A1 | |
| SCHEMBL2202782 | 0.72 | TTR (0.41) | TDP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7094488 | 0.69 | RAB9A (0.38) | RAB9AMEN1KMT2APKMRXFP1 | |
| SCHEMBL973209 | 0.69 | IKBKB (0.40) | RAB9AMEN1KMT2ARXFP1KDM4E | |
| SCHEMBL11319297 | 0.66 | ALDH1A1 (0.42) | TDP1RAB9AMEN1KMT2AHTT | |
| SCHEMBL3234460 | 0.65 | NPC1 (0.41) | TDP1RAB9AMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250182-A | Pharmaceutical composition containing acridone compounds and method of using same | BURROUGHS WELLCOME CO. (US) | 1981-02-10 | — | — | US | disclosed |