SCHEMBL1132771

SCHEMBL1132771

CCCCCCCCCC=CCc1ccc2cccc(O)c2n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 3/20 0.47
F3 P13726 3/20 0.47
MMP2 P08253 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
ALOX15 P16050 1/20 0.47
ECE1 P42892 1/20 0.47
SGMS1 Q86VZ5 1/20 0.47
SGMS2 Q8NHU3 1/20 0.47
MUS81 Q96NY9 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
BID P55957 3/20 0.44
BCL2L1 Q07817 3/20 0.44
MCL1 Q07820 3/20 0.44
BAK1 Q16611 3/20 0.44
METAP2 P50579 1/20 0.42
PDE10A Q9Y233 2/20 0.39
PLAU P00749 1/20 0.39
NCF1 P14598 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11059362 0.90 F7 (0.53) F7F3MMP2HSD17B10KDM4E
SCHEMBL8605536 0.87 BID (0.53) F7F3MMP2HSD17B10KDM4E
SCHEMBL11849124 0.80 KCNH2 (0.59) HSD17B10SAE1BIDBCL2L1MCL1
SCHEMBL2877334 0.80 KCNH2 (0.59) HSD17B10SAE1BIDBCL2L1MCL1
SCHEMBL10349305 0.80 KCNH2 (0.59) HSD17B10SAE1BIDBCL2L1MCL1
SCHEMBL7875801 0.80 KCNH2 (0.59) HSD17B10SAE1BIDBCL2L1MCL1
SCHEMBL8898779 0.80 KCNH2 (0.59) HSD17B10SAE1BIDBCL2L1MCL1
SCHEMBL1132770 0.80 MEN1 (0.52) KDM4EMAPTCYP1A2
SCHEMBL1132773 0.80 MEN1 (0.52) KDM4EMAPTCYP1A2
SCHEMBL11685736 0.79 ALDH1A1 (0.41) F7F3MMP2HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4568526-A CONTACTING WITH ORGANIC MEDIUM CONTAINING DILUENT AND EXTRACTANT, STRIPPING FROM ORGANIC PHASE SOCIETE MINIERE ET METALLURGIQUE DE PENARROYA (FR) 1986-02-04 US claimed
US-4389379-A USING OXINE DERIVATIVES SOCIETE MINIERE ET METALLURGIQUE DE PENARROYA (FR) 1983-06-21 US claimed
EP-2102317-B1 ADDITIVE, FUEL COMPOSITION, METHOD AND USE INNOSPEC LTD (GB) 2018-10-17 EP disclosed
EP-1899440-B1 FUEL COMPOSITION INNOSPEC DEUTSCHLAND GMBH (DE) 2016-06-15 EP disclosed
US-9255233-B2 Fuel additive compositions INNOSPEC LIMITED (GB) 2016-02-09 US disclosed
US-8870981-B2 Additive fuel composition, and method of use thereof INNOSPEC LIMITED (GB) 2014-10-28 US disclosed
US-20130183628-A1 ADDITIVE FUEL COMPOSITION, AND METHOD OF USE THEREOF INNOSPEC LIMITED (GB) 2013-07-18 US disclosed
US-20110223547-A1 FUEL ADDITIVE COMPOSITIONS INNOSPEC LIMITED (GB) 2011-09-15 US disclosed
EP-2287277-A1 Composition Innospec Deutschland GmbH (DE) 2011-02-23 EP disclosed
US-20100151396-A1 COMPOSITION, METHOD AND USE INNOSPEC LIMITED (GB) 2010-06-17 US disclosed
EP-2102317-A1 COMPOSITION, METHOD AND USE Innospec Limited (GB) 2009-09-23 EP disclosed
WO-2004055136-A1 USE OF METAL TO PREVENT SPARK PLUGS FOULING FROM IRON THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 2004-07-01 WO disclosed
EP-1047755-B1 FUEL ADDITIVES ASS OCTEL (GB) 2003-04-23 EP disclosed
US-6488725-B1 REGENERATING FILTER TRAP BY ADDING SYNERGISTIC MIXTURE OF IRON COMPOUND AND BARIUM AND/OR STRONTIUM COMPOUND BEFORE OR DURING COMBUSTION; DIESEL ENGINES THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 2002-12-03 US disclosed
EP-1230327-A1 FUEL ADDITIVE FOR THE PREVENTION OF VALVE SEAT RECESSION The Associated Octel Company Limited (GB) 2002-08-14 EP disclosed
WO-2001016257-A1 FUEL ADDITIVE FOR THE PREVENTION OF VALVE SEAT RECESSION THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 2001-03-08 WO disclosed
EP-1047755-A1 FUEL ADDITIVES THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 2000-11-02 EP disclosed
WO-1999036488-A1 FUEL ADDITIVES THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 1999-07-22 WO disclosed
US-4568526-A CONTACTING WITH ORGANIC MEDIUM CONTAINING DILUENT AND EXTRACTANT, STRIPPING FROM ORGANIC PHASE SOCIETE MINIERE ET METALLURGIQUE DE PENARROYA (FR) 1986-02-04 US disclosed
US-4389379-A USING OXINE DERIVATIVES SOCIETE MINIERE ET METALLURGIQUE DE PENARROYA (FR) 1983-06-21 US disclosed