SCHEMBL1132773

SCHEMBL1132773

CCCCCCCCCCC=Cc1ccc2cccc(O)c2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 15/20 0.52
KMT2A Q03164 15/20 0.52
NPC1 O15118 14/20 0.52
CD74 P04233 1/20 0.51
MIF P14174 1/20 0.51
RAB9A P51151 9/20 0.50
AGTR1 P30556 5/20 0.50
HSP90AA1 P07900 4/20 0.50
ECE2 P0DPD6 2/20 0.50
CASP3 P42574 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
KDM4E B2RXH2 4/20 0.49
MAPT P10636 3/20 0.49
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HTT P42858 2/20 0.49
POLB P06746 1/20 0.49
OPRK1 P41145 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132770 1.00 MEN1 (0.52) MEN1KMT2ANPC1CD74MIF
SCHEMBL11053333 0.87 USP9X (0.46) MEN1KMT2ANPC1CD74MIF
SCHEMBL1132771 0.80 F7 (0.47) KDM4EMAPTCYP1A2
SCHEMBL11059362 0.80 F7 (0.53) KDM4EMAPT
SCHEMBL3265939 0.80 CCR1 (0.44) HSP90AA1KDM4EMAPTLMNASMN1; SMN2
SCHEMBL29970018 0.79 KCNH2 (0.44) KDM4EMAPTSMN1; SMN2NFKB1
SCHEMBL11053329 0.79 LTB4R (0.41) KDM4EMAPT
SCHEMBL16107255 0.78 KMT2A (0.61) MEN1KMT2ANPC1CD74MIF
SCHEMBL8605536 0.77 BID (0.53) KDM4EMAPT
SCHEMBL22501441 0.76 KDM4E (0.50) MEN1KMT2ANPC1RAB9AECE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102317-B1 ADDITIVE, FUEL COMPOSITION, METHOD AND USE INNOSPEC LTD (GB) 2018-10-17 EP disclosed
EP-1899440-B1 FUEL COMPOSITION INNOSPEC DEUTSCHLAND GMBH (DE) 2016-06-15 EP disclosed
US-9255233-B2 Fuel additive compositions INNOSPEC LIMITED (GB) 2016-02-09 US disclosed
CN-101636476-B Composition, method and purposes INNOSPEC LTD. (GB) 2015-08-12 CN disclosed
US-8870981-B2 Additive fuel composition, and method of use thereof INNOSPEC LIMITED (GB) 2014-10-28 US disclosed
US-20130183628-A1 ADDITIVE FUEL COMPOSITION, AND METHOD OF USE THEREOF INNOSPEC LIMITED (GB) 2013-07-18 US disclosed
US-20110223547-A1 FUEL ADDITIVE COMPOSITIONS INNOSPEC LIMITED (GB) 2011-09-15 US disclosed
EP-2358848-A1 IMPROVEMENT IN OR RELATING TO FUEL ADDITIVE COMPOSITIONS Innospec Limited (GB) 2011-08-24 EP disclosed
EP-2287277-A1 Composition Innospec Deutschland GmbH (DE) 2011-02-23 EP disclosed
US-20100151396-A1 COMPOSITION, METHOD AND USE INNOSPEC LIMITED (GB) 2010-06-17 US disclosed
WO-2007007191-A1 COMPOSITION INNOSPEC DEUTSCHLAND GMBH (DE) 2007-01-18 WO disclosed
EP-1230327-B1 FUEL ADDITIVE FOR THE PREVENTION OF VALVE SEAT RECESSION ASS OCTEL (GB) 2006-06-07 EP disclosed
WO-2005087901-A2 FUEL ADDITIVE COMPOSITION HAVING ANTIKNOCK PROPERTIES INNOSPEC LIMITED (GB) 2005-09-22 WO disclosed
WO-2004055136-A1 USE OF METAL TO PREVENT SPARK PLUGS FOULING FROM IRON THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 2004-07-01 WO disclosed
EP-1047755-B1 FUEL ADDITIVES ASS OCTEL (GB) 2003-04-23 EP disclosed
US-6488725-B1 REGENERATING FILTER TRAP BY ADDING SYNERGISTIC MIXTURE OF IRON COMPOUND AND BARIUM AND/OR STRONTIUM COMPOUND BEFORE OR DURING COMBUSTION; DIESEL ENGINES THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 2002-12-03 US disclosed
EP-1230327-A1 FUEL ADDITIVE FOR THE PREVENTION OF VALVE SEAT RECESSION The Associated Octel Company Limited (GB) 2002-08-14 EP disclosed
WO-2001016257-A1 FUEL ADDITIVE FOR THE PREVENTION OF VALVE SEAT RECESSION THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 2001-03-08 WO disclosed
EP-1047755-A1 FUEL ADDITIVES THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 2000-11-02 EP disclosed
WO-1999036488-A1 FUEL ADDITIVES THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 1999-07-22 WO disclosed