Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327758 | 1.00 | PGR (0.36) | PGRL3MBTL1TDP1AKR1C3LMNA | |
| SCHEMBL7771434 | 0.78 | TSHR (0.42) | L3MBTL1LMNAF2CES2CES1 | |
| SCHEMBL9021031 | 0.78 | TSHR (0.42) | L3MBTL1LMNAF2CES2CES1 | |
| SCHEMBL7771436 | 0.78 | TSHR (0.42) | L3MBTL1LMNAF2CES2CES1 | |
| SCHEMBL11329134 | 0.76 | SMN1; SMN2 (0.44) | LMNACES2CES1TSHRALDH1A1 | |
| SCHEMBL11329136 | 0.76 | SMN1; SMN2 (0.44) | LMNACES2CES1TSHRALDH1A1 | |
| SCHEMBL11333630 | 0.74 | LMNA (0.42) | L3MBTL1LMNACES2CES1TSHR | |
| SCHEMBL11306263 | 0.74 | ELANE (0.41) | L3MBTL1TDP1LMNAF2CES2 | |
| SCHEMBL11251665 | 0.74 | LMNA (0.42) | L3MBTL1LMNACES2CES1TSHR | |
| SCHEMBL9330060 | 0.74 | LMNA (0.42) | L3MBTL1LMNACES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256739-A | 7β-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and antibacterial compositions and methods using them | CIBA-GEIGY CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |