Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11328030 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1HTTCA2TSHR | |
| SCHEMBL8862881 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TDP1CA2SMN1; SMN2MMP1 | |
| SCHEMBL8862880 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TDP1CA2SMN1; SMN2MMP1 | |
| SCHEMBL12906546 | 0.77 | NPSR1 (0.46) | ALDH1A1TDP1TSHRCYP2C19NPSR1 | |
| SCHEMBL11417638 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TDP1HTTCA2SMN1; SMN2 | |
| SCHEMBL11417640 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TDP1HTTCA2SMN1; SMN2 | |
| SCHEMBL11273548 | 0.73 | — | — | |
| SCHEMBL28637253 | 0.72 | APOBEC3A (0.46) | ALDH1A1TDP1CA2TSHRNPSR1 | |
| SCHEMBL18885573 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TDP1CA2 | |
| SCHEMBL21572866 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TDP1CA2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021485-A1 | INDOLE DERIVATIVES AND THEIR METAL CONJUGATES AND USES THEREOF | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2011-01-27 | — | — | US | disclosed |
| US-20110021485-A1 | INDOLE DERIVATIVES AND THEIR METAL CONJUGATES AND USES THEREOF | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2011-01-27 | — | — | US | disclosed |
| US-7781480-B2 | Indole derivatives and their metal conjugates and uses thereof | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2010-08-24 | — | — | US | disclosed |
| US-20080242652-A1 | Indole derivatives and their metal conjugates and uses thereof | VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) | 2008-10-02 | — | — | US | disclosed |
| US-4303689-A | Flavoring with pyrazine derivatives | FIRMENICH SA (CH) | 1981-12-01 | — | — | US | disclosed |
| US-4138410-A | Flavoring agent | FIRMENICH & CIE (CH) | 1979-02-06 | — | — | US | disclosed |
| US-4126618-A | FLAVOR ADDITIVES FOR FOODS AND BEVERAGES | FIRMENICH & CIE (CH) | 1978-11-21 | — | — | US | disclosed |
| US-4085109-A | Pyridine sulfur flavoring agents | FIRMENICH & CIE (CH) | 1978-04-18 | — | — | US | disclosed |
| US-3989713-A | Pyrrylmethylthio flavoring agents | FIRMENICH & CIE (CH) | 1976-11-02 | — | — | US | disclosed |
| US-3952026-A | FLAVOR ADDITIVE FOR FOODS AND BEVERAGES | FIRMENICH & CIE (CH) | 1976-04-20 | — | — | US | disclosed |
| US-3952024-A | FLAVOR ADDITIVE FOR FOODS AND BEVERAGES | FIRMENICH & CIE (CH) | 1976-04-20 | — | — | US | disclosed |
| US-3943260-A | TETRAHYDRO-THIO-PHEN-3-ONES | FIRMENICH & CIE (CH) | 1976-03-09 | — | — | US | disclosed |
| US-3931245-A | FURYLALKYLTHIOL CARBOXYLATES | FIRMENICH & CIE (CH) | 1976-01-06 | — | — | US | disclosed |
| US-3931166-A | FLAVORANTS | FIRMENICH & CIE (CH) | 1976-01-06 | — | — | US | disclosed |
| US-3931246-A | FURYLALKYL-THIOETHERS | FIRMENICH & CIE (CH) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021485-A1 | INDOLE DERIVATIVES AND THEIR METAL CONJUGATES AND USES THEREOF | IDO1, IDO2, INMT | ALDH1A1 2752/4885TDP1 2460/4885HTT 1011/4885 |
| US-20080242652-A1 | Indole derivatives and their metal conjugates and uses thereof | IDO1, IDO2, INMT | ALDH1A1 2752/4885TDP1 2460/4885HTT 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.