Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11328030 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TDP1CA2 | |
| SCHEMBL11328029 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TDP1CA2 | |
| SCHEMBL3375511 | 0.63 | — | — | |
| SCHEMBL19883375 | 0.63 | — | — | |
| SCHEMBL169095 | 0.62 | SLC7A5 (0.36) | SLC7A5 | |
| SCHEMBL169094 | 0.62 | SLC7A5 (0.36) | SLC7A5 | |
| SCHEMBL14403015 | 0.61 | ALDH1A1 (0.40) | ALDH1A1TDP1CA2SLC7A5 | |
| SCHEMBL23550736 | 0.60 | — | — | |
| SCHEMBL93309 | 0.60 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL28836144 | 0.60 | ALDH1A1 (0.88) | ALDH1A1TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670484-B2 | Methods and compositions | BICYCLE THERAPEUTICS LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |
| US-9657288-B2 | Connector compound peptide phage display | BICYCLE THERAPEUTICS LIMITED (GB) | 2017-05-23 | — | — | US | disclosed |