SCHEMBL11328132

SCHEMBL11328132

Clc1ccc2sc(-c3c[c]ccc3)nc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.45
▸ MGAM O43451 1/20 0.45
▸ SI P14410 1/20 0.45
▸ MGAM2 Q2M2H8 1/20 0.45
▸ SENP7 Q9BQF6 2/20 0.44
▸ HTT P42858 1/20 0.44
▸ CASP3 P42574 1/20 0.44
▸ SENP8 Q96LD8 1/20 0.44
▸ SENP6 Q9GZR1 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ LOXL2 Q9Y4K0 1/20 0.43
▸ IDO1 P14902 1/20 0.43
▸ APP P05067 2/20 0.42
▸ KDM4E B2RXH2 2/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ NFKB1 P19838 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ NFKB2 Q00653 2/20 0.41
▸ RELA Q04206 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28599530 0.82 KDM4E (0.57) GAAMGAMSIMGAM2SENP7
SCHEMBL15515272 0.81 MGAM (0.48) GAAMGAMSIMGAM2SENP7
SCHEMBL8717233 0.80 RAB9A (0.56) GAASMN1; SMN2APPKDM4ENPC1
SCHEMBL28501886 0.80 RAB9A (0.50) GAAMGAMSIMGAM2SENP7
SCHEMBL11635588 0.76 GAA (0.50) GAAMGAMSIMGAM2SENP7
SCHEMBL24366502 0.75 NPC1 (0.66) GAAMGAMSIMGAM2SENP7
SCHEMBL8704440 0.74 KDM4E (0.60) GAAMGAMSIMGAM2SENP7
SCHEMBL31145129 0.74 KDM4E (0.60) GAAMGAMSIMGAM2SENP7
SCHEMBL12470519 0.73 GAA (0.56) GAAMGAMSIMGAM2SENP7
SCHEMBL12470432 0.73 MAPT (0.61) GAAMGAMSIMGAM2SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4308194-A Heterocyclic benzoate ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1981-12-29 — — US disclosed
US-4256626-A 2-BENZIMIDAZOLYL-, 2-BENZOTHIAZOLYL-, OR 2-INDOLYL-PHENYL DERIVATIVES LINKED TO A 2-HYDROXYBENZOPHENONE EASTMAN KODAK COMPANY (US) 1981-03-17 — — US disclosed
US-4187213-A CONTAINING BENZOTHIAZOLE, BENZIMIDAZOLE, BENZOTHIAZOLE OR INDOLE RING AND PIPERIDINE RING EASTMAN KODAK COMPANY (US) 1980-02-05 — — US disclosed
US-4174321-A POLYMERIC MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1979-11-13 — — US disclosed
US-4172081-A Benzotriazole ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-10-23 — — US disclosed
US-4166803-A Heterocyclic benzoate ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1979-09-04 — — US disclosed
US-4162254-A Benzoxazole ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-07-24 — — US disclosed
US-4127501-A BENZOXAZOLE, BENZOTHIAZOLE, BENZIMIDAZOLE, BENZOTRIAZOLE OR INDOLE DERIVATIVES EASTMAN KODAK COMPANY (US) 1978-11-28 — — US disclosed
US-4116929-A POLYESTERS EASTMAN KODAK COMPANY (US) 1978-09-26 — — US disclosed
US-4115348-A DEGRADATION INHIBITORS EASTMAN KODAK COMPANY (US) 1978-09-19 — — US disclosed
US-4096115-A Ultraviolet light stabilized polymers EASTMAN KODAK COMPANY (US) 1978-06-20 — — US disclosed
US-4075220-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1978-02-21 — — US disclosed
US-4065427-A Polychromophoric heterocyclic ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1977-12-27 — — US disclosed
US-4017508-A POLYMERS EASTMAN KODAK COMPANY (US) 1977-04-12 — — US disclosed
US-4000148-A POLYMERS EASTMAN KODAK COMPANY (US) 1976-12-28 — — US disclosed
US-3981822-A HETEROCYCLIC COMPOUNDS EASTMAN KODAK COMPANY (US) 1976-09-21 — — US disclosed
US-3957813-A BENZOXAZOLYL PHENYL AROMATIC ESTER COMPOUNDS AND THEIR USE AS ULTRAVIOLET STABILIZERS IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1976-05-18 — — US disclosed
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