SCHEMBL8717233

SCHEMBL8717233

[c]1cccc(-c2nc3ccccc3s2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 9/20 0.56
▸ NPC1 O15118 6/20 0.56
▸ KDM4E B2RXH2 5/20 0.56
▸ APP P05067 5/20 0.54
▸ MAPT P10636 4/20 0.54
▸ ALDH1A1 P00352 3/20 0.54
▸ LMNA P02545 2/20 0.54
▸ GLA P06280 2/20 0.54
▸ GAA P10253 2/20 0.54
▸ MMP9 P14780 2/20 0.54
▸ MMP8 P22894 2/20 0.54
▸ SMN1; SMN2 Q16637 4/20 0.54
▸ MEN1 O00255 4/20 0.54
▸ KMT2A Q03164 4/20 0.54
▸ NFKB1 P19838 3/20 0.54
▸ NFKB2 Q00653 3/20 0.54
▸ RELA Q04206 3/20 0.54
▸ TP53 P04637 1/20 0.54
▸ POLB P06746 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylbenzo[D]Thiazole SCHEMBL27839442 0.82 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
SCHEMBL713164 0.81 RAB9A (0.66) RAB9ANPC1KDM4EAPPMAPT
SCHEMBL11328132 0.80 GAA (0.45) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL30988131 0.80 RAB9A (0.75) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL94005 0.80 RAB9A (0.75) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL29986751 0.78 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL2453217 0.78 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL27607988 0.78 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL29928313 0.78 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL27949942 0.78 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9624193-B2 Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component TOSOH CORPORATION (JP) 2017-04-18 — — US disclosed
US-9379336-B2 Compounds for use in light emitting devices NITTO DENKO CORPORATION (JP) 2016-06-28 — — US disclosed
US-20150329544-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT TOSOH CORPORATION (JP) 2015-11-19 — — US disclosed
US-9120773-B2 Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component TOSOH CORPORATION (JP) 2015-09-01 — — US disclosed
EP-2818462-A1 Cyclic azine derivatives, processes for producing these, and organic electrolumiscent element containing these as component TOSOH CORPORATION (JP) 2014-12-31 — — EP disclosed
CN-103975456-A Light-emitting devices comprising nanostructures NITTO DENKO CORP 2014-08-06 — — CN disclosed
US-20140061614-A1 COMPOUNDS FOR USE IN LIGHT EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2014-03-06 — — US disclosed
US-20120214993-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT SAGAMI CHEMICAL RESEARCH INSTITUTE, (JP) 2012-08-23 — — US disclosed
EP-2468731-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT Tosoh Corporation (JP) 2012-06-27 — — EP disclosed
US-5847006-A Therapeutic guanidines CAMBRIDGE NEUROSCIENCE, INC. (US) 1998-12-08 — — US disclosed
EP-0746316-A4 THERAPEUTIC GUANIDINES CAMBRIDGE NEUROSCIENCE INC (US) 1997-12-10 — — EP disclosed
EP-0746316-A1 THERAPEUTIC GUANIDINES CAMBRIDGE NEUROSCIENCE, INC. (US) 1996-12-11 — — EP disclosed
WO-1995014467-A1 THERAPEUTIC GUANIDINES CAMBRIDGE NEUROSCIENCE, INC. (US) 1995-06-01 — — WO disclosed
US-4166803-A Heterocyclic benzoate ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1979-09-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150329544-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT CPNE4, EPB41, AZI2 RAB9A 1136/4885NPC1 3259/4885KDM4E 577/4885
US-20120214993-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT CPNE4, EPB41, AZI2 RAB9A 1136/4885NPC1 3259/4885KDM4E 577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback